Pseudolaric Acid B Combats Drug-Resistant Candida albicans Infection via Dual-Action Mechanisms of Direct Antifungals and Vaginal Microbiota Restoration. [PDF]
We propose a novel therapeutic approach against fungal infection: Pseudolaric acid B directly eradicates C. albicans via Erg11 inhibition and uniquely, restores vaginal microecological homeostasis by promoting probiotic lactobacilli, addressing both the pathogen and the dysbiotic environment.
Shao T, Zhang Y, Xue B, Chu W.
europepmc +2 more sources
Gynecologic conditions in the context of incarceration: A scoping review. [PDF]
Abstract Background More than 740 000 people identified as female at intake were incarcerated globally as of 2022, reflecting a 60% global increase since the year 2000, with a concomitant increase in gynecologic conditions experienced behind bars.
Wise MK +6 more
europepmc +2 more sources
Vaginal-Derived Potential Probiotics and Their Postbiotics Alleviate Aerobic Vaginitis via Suppressing TLR4/MyD88/NF-κB Signalling Pathway and Potentially Enhancing Vaginal Barrier. [PDF]
Consolidated diagram of the mechanism by which L. crispatus YBR‐01, L. plantarum YBR‐01, and their postbiotics improve AV progression. ABSTRACT Antibiotic therapy is currently challenged by drug resistance and high recurrence in aerobic vaginitis (AV), making it urgent to seek novel strategies. In this study, we selected two potential probiotic strains
Tian M +7 more
europepmc +2 more sources
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Epidemiology of Mycoplasma genitalium Infections of the Genitourinary Tract Among Attendees of STI Clinic in Hangzhou, China. [PDF]
ABSTRACT Objective This study aimed to investigate the prevalence, associated clinical manifestations, and co‐infection patterns of Mycoplasma genitalium (MG) infection among patients attending Venereal Disease, Urology, and Gynecology clinics in Hangzhou, China.
Qiu X, Shi J, Gu H, Liu J.
europepmc +2 more sources
Background and Objectives: Vulvovaginal infections pose significant health challenges for women, necessitating effective treatment approaches. This retrospective observational study aimed at investigating the efficacy of collagen-based vaginal ovules ...
Nicoletta De Rosa +4 more
doaj +1 more source
Inflammatory vaginitis in women on long-term rituximab treatment for autoimmune disorders
Background Consequences of long-term B cell depletion with rituximab are not well understood. We describe inflammatory vaginitis as a potential side effect of long-term rituximab treatment, distinct from previously described vulvovaginal pyoderma ...
Laura Yockey +8 more
doaj +1 more source
Hubungan Tingkat Stres dengan Gejala Vaginitis pada Mahasiswi Program Studi Kedokteran FK UNAND 2019
Tujuan: untuk mengetahui hubungan antara tingkat stres dengan gejala vaginitis pada mahasisiwi program studi Fakultas Kedokteran Universitas Andalas Angkatan 2019.
Melsi Megawati +2 more
doaj +1 more source
Mixed vaginitis is the result of the simultaneous presence of different pathogenic processes mediated by at least two types of vaginal pathogens. Among the various types of mixed vaginitis presentations, bacterial vaginosis (BV) plus vulvovaginal ...
Bingbing Xiao +4 more
doaj +1 more source
Comparison of viromes in vaginal secretion from pregnant women with and without vaginitis
Background Although some studies have investigated the bacterial community in vaginal tract of pregnant women, there are few reports about the viral community (virome) in this type of microenvironment.
He-Teng Zhang +4 more
doaj +1 more source

