The presence of the putative Gardnerella vaginalis sialidase A gene in vaginal specimens is associated with bacterial vaginosis biofilm [PDF]
Bacterial vaginosis (BV) is a difficult-to-treat recurrent condition in which health-associated lactobacilli are outnumbered by other anaerobic bacteria, such as Gardnerella vaginalis. Certain genotypes of G. vaginalis can produce sialidase, while others
Buyze, Jozefien+7 more
core +14 more sources
Genome sequences of 15 Gardnerella vaginalis strains isolated from the vaginas of women with and without bacterial vaginosis [PDF]
Gardnerella vaginalis is a predominant species in bacterial vaginosis, a dysbiosis of the vagina that is associated with adverse health outcomes, including preterm birth.
Lek, Sai+7 more
core +9 more sources
Association between obesity and bacterial vaginosis as assessed by Nugent score [PDF]
Background Bacterial vaginosis is one of the most common vaginal conditions in the U.S. Recent studies have suggested obese women have an abnormal microbiota reminiscent of BV; however, few studies have investigated the prevalence of bacterial vaginosis
Allsworth, Jenifer E.+4 more
core +1 more source
Prevalence of Bacterial Vaginosis and Associated Factors among Pregnant Women Attending at Bugando Medical Centre, Mwanza, Tanzania [PDF]
Bacterial vaginosis (BV) is an extremely common reproductive tract condition worldwide with reported high prevalence among African population. Factors associated with this condition include preterm labour, premature rupture of membranes, preterm delivery
Gumodoka, Balthazar+8 more
core +2 more sources
Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. [PDF]
OBJECTIVES: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy ...
Baisley, Kathy+8 more
core +1 more source
The significance of Lactobacillus crispatus and L. vaginalis for vaginal health and the negative effect of recent sex: a cross-sectional descriptive study across groups of African women [PDF]
Background: Women in sub-Saharan Africa are vulnerable to acquiring HIV infection and reproductive tract infections. Bacterial vaginosis (BV), a disruption of the vaginal microbiota, has been shown to be strongly associated with HIV infection.
Gilles F Ndayisaba+12 more
core +2 more sources
Public health approach to prevent cervical cancer in HIV-infected women in Kenya : issues to consider in the design of prevention programs [PDF]
Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds HPV persistence, thereby increasing the risk for cervical ...
Callens, Steven+4 more
core +3 more sources
Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard+156 more
core +2 more sources
Distribution of human papillomaviruses and bacterial vaginosis in HIV positive women with abnormal cytology in Mombasa, Kenya [PDF]
Background: HPV is the major etiological factor in the causal pathway for cervical cancer, which is the leading cancer among women in sub-Saharan Africa. HIV is associated with a higher prevalence and a broader range of high-risk HPV genotypes.
Harebottle, Ronald+4 more
core +2 more sources
Immunoglobulin A response against Gardnerella vaginalis hemolysin and sialidase activity in bacterial vaginosis [PDF]
OBJECTIVE: The aim of this study was to investigate the correlation between the immunoglobulin A immune response to Gardnerella vaginalis hemolysin and sialidase activity in vaginal fluids from patients with bacterial vaginosis.
Cauci, S.+5 more
core +1 more source