Results 141 to 150 of about 5,384 (285)

Tropical cyclone activity predicts autumn vagrancy of Nearctic birds on a remote North Atlantic island. [PDF]

BMC Zool
Monticelli D.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Uncovering genetic population structure in the Endangered northern rockhopper penguin (Eudyptes moseleyi) across islands in the Southern Atlantic and Indian oceans. [PDF]

BMC Genomics
Ritchie-Parker H, Ball A, Glass T, Costanzi JM, Boulinier T, Gamble A, Ghazali M, Keegan K, Barbraud C, Bost C, Bost C, Cleeland J, Clessin A, Connan M, Delord K, Dilley B, Glass T, Jones CW, Moore P, Lawrence K, LeBouard F, Osborne A, Phillips RA, Ratcliffe N, Repetto J, Risi M, Ryan PG, Spolander B, Swain S, Swain W, Tornos J, Whittle A, Senn H, Steinfurth A.   +33 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

A high-quality reference genome for the ornate shrew (Sorex ornatus). [PDF]

J Hered
Linn IJ, Escalona M, Nguyen O, Marimuthu MPA, Chumchim N, Fairbairn CW, Seligmann W, Beraut E, Conroy CJ, Bowie RCK, Nachman MW.   +10 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

14,15-dihydroclerodin (C₂₄H₃₆O₇) induced cell cycle delay, antimitotic and cytotoxic effects in Allium cepa L. root tip cells. [PDF]

Sci Rep
Ghosh P, Roy S, Ray S.
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Starch-Coated Superparamagnetic Fe₃O₄ Nanoparticles: From Physicochemical Characterization to Cytogenetic Assessment in <i>Triticum aestivum</i> L. [PDF]

Nanomaterials (Basel)
Racuciu M, Barbu-Tudoran L, Grigoras M, Brinza F, Oancea S, Creanga D.   +5 more
europepmc   +1 more source