DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
New Additions to the Mammal List Documented in the Portuguese Red Data Book. [PDF]
Mathias MDL +14 more
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
In-silico receptor interactions, phytochemical fingerprint and biological activities of Matricaria chamomilla flower extract and the main components. [PDF]
Ayhan BS, Yalçin E, Çavuşoğlu K.
europepmc +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Identification and field testing of sex-attractant semiochemicals produced by male deer mice, Peromyscus maniculatus. [PDF]
Varner E +7 more
europepmc +1 more source
A study on the effect of Hypericum perforatum L. extract on vanadium toxicity in Allium cepa L. [PDF]
Macar TK, Macar O.
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Exogenous application of mycotoxin fusaric acid improve the morphological, cytogenetic, biochemical and anatomical parameters in salt (NaCl) stressed Allium cepa L. [PDF]
Çavuşoğlu K, Çavuşoğlu D.
europepmc +1 more source
Naringin and Naringenin Functionalized Silver Nanoparticles: Synthesis, Characterization and Biological Evaluation. [PDF]
Măriuț OA +9 more
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Laws regulating the movement, residence, employment, and labor of the poor, and especially of poor African Americans in states with burgeoning free populations, demonstrate how mobility, when enacted by the poor and by non-whites, was classified as a criminal action in the eighteenth- and nineteenth-century United States. In the Upper South especially,
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