Results 161 to 170 of about 83,408 (314)

Self‐limited familial focal epilepsy caused by ANK2 variants: A potentially under‐recognized condition

open access: yesEpilepsia Open, EarlyView.
Abstract The Ankyrin 2 (ANK2) gene encodes the ankyrin‐B protein (ANKB), which is involved in the organization and stability of membrane ion channels, transporters, and receptors in cardiomyocytes and neurons. Variants in ANK2 genes are initially reported in long QT syndrome and autism.
Po‐Hsi Lin   +5 more
wiley   +1 more source

Clinically indicated electrical stimulation strategies to treat patients with medically refractory epilepsy. [PDF]

open access: yes, 2018
Focal epilepsies represent approximately half of all diagnoses, and more than one-third of these patients are refractory to pharmacologic treatment.
Gurkoff, Gene   +5 more
core  

Intracranial stimulation for pediatric refractory epilepsy: A single institutional experience using evolving therapies

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Neuromodulation for pediatric refractory epilepsy (PRE) is preferred when the seizure onset zone is not amenable to surgical resection, due to multifocal onset or involvement of eloquent cortex. Given its rapidly evolving landscape, we describe our institutional experience with neurostimulation therapies including deep brain ...
Rohin Singh   +9 more
wiley   +1 more source

Real‐world effectiveness and tolerability of cenobamate in drug‐resistant epilepsy: A retrospective analysis of the patients included into the Early Access Programs (EAP) in Germany, France, and United Kingdom

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Investigate real‐world outcomes in drug‐resistant epilepsy (DRE) patients treated with cenobamate as adjunctive treatment to other antiseizure medications (ASMs) within the Early Access Programs (EAP) in Germany, France, and the United Kingdom.
Sylvain Rheims   +13 more
wiley   +1 more source

Primary Sjögren syndrome‐related peripheral neuropathy: A systematic review and meta‐analysis

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 255-265, January 2023., 2023
The pooled prevalence of peripheral neuropathy in primary Sjögren syndrome (pSS) is estimated to be 15% (95% confidence interval = 11%–21%). pSS‐related neuropathy usually manifests in the 6th decade of life. The commonest type is distal axonal polyneuropathy, followed by sensory ganglionopathy. Abstract Background and purpose Primary Sjögren syndrome (
Andreas Liampas   +10 more
wiley   +1 more source

Drug‐resistant epilepsy and mortality—Why and when do neuromodulation and epilepsy surgery reduce overall mortality

open access: yesEpilepsia, Volume 63, Issue 12, Page 3020-3036, December 2022., 2022
Abstract Patients with drug‐resistant epilepsy have an increased mortality rate, with the majority of deaths being epilepsy related and 40% due to sudden unexpected death in epilepsy (SUDEP). The impact of epilepsy surgery on mortality has been investigated since the 1970s, with increased interest in this field during the past 15 years.
Sylvain Rheims   +2 more
wiley   +1 more source

Noninvasive brain stimulation as focal epilepsy treatment in the hospital, clinic, and home

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Noninvasive brain stimulation (NIBS) provides a treatment option for patients not eligible for surgical intervention or who seek low‐risk approaches and may be used in the hospital, clinic, and at home. Our objective is to summarize our single‐center experience with multiple NIBS approaches for the treatment of focal epilepsy ...
Karimul Islam   +7 more
wiley   +1 more source

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