Results 161 to 170 of about 95,247 (354)
Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study
Epilepsia Open, EarlyView.Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell +11 more
wiley +1 more source
The importance of methodological context in pediatric vagus nerve stimulation outcome reporting
Epilepsia, EarlyView.
Thiemo F. Dinger +2 more
wiley +1 more source
Ultra‐refractory epilepsy: The newly described entity
Epilepsia Open, EarlyView.Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek +13 more
wiley +1 more source
Reversible sleep‐related stridor during vagus nerve stimulation
, 2010 Erik K. St. Louis, Kevin Faber
openalex +1 more source
Epilepsia Open, EarlyView.Abstract Objective The long‐term effects of epilepsy surgery (ES) or vagus nerve stimulation (VNS) on antiseizure medication (ASM) usage and status epilepticus (SE) diagnosis in real‐world pediatric drug‐resistant epilepsy (DRE) populations remain unclear. This study aimed to provide a more comprehensive understanding of how VNS and ES affect ASM usage
Jooyoung Lee +3 more
wiley +1 more source
Cognitive safety under epicranial cortex stimulation of the epileptic focus
Epilepsia Open, EarlyView.Abstract Epicranial focal cortex stimulation (FCS) is a new CE‐certified treatment for pharmacoresistant focal epilepsy. In a multicenter observational trial, we report cognitive tolerability in 11 patients with pharmacoresistant epilepsy undergoing epicranial focal cortex stimulation (eFCS) over the predominant seizure focus (left temporal (N = 4 ...
Kathrin Wagner +10 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen +6 more
wiley +1 more source
Food Frontiers, EarlyView.‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski +7 more
wiley +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Food Frontiers, EarlyView.Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source