Results 161 to 170 of about 96,565 (355)

Real‐world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2‐q13.1 duplication and deletion syndromes: A multicenter study

open access: yesEpilepsia Open, EarlyView.
Abstract This multicenter retrospective study evaluated the effectiveness and safety of highly purified cannabidiol (CBD) in 22 patients with 15q11.2‐q13.1 duplication or deletion syndromes (15q‐DDS), including 12 with 15q duplication syndrome (dup15q) and 10 with Angelman syndrome (AS). Median (interquartile range [IQR]) age at CBD initiation was 14.5
Emanuele Cerulli Irelli   +14 more
wiley   +1 more source

Effectiveness of adjunctive low‐dose clobazam in adults with focal drug‐resistant epilepsy and incomplete response to cenobamate: A real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is a highly effective antiseizure medication (ASM) for focal drug‐resistant epilepsy (DRE); nevertheless, even with CNB treatment and optimized therapy, a substantial proportion of patients continued to experience seizures.
Ilaria Ciullo   +8 more
wiley   +1 more source

Transoral Styloidectomy Approach: A Systematic Review and Enhanced Endoscopic Approach

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Synthesize transoral styloidectomy approaches, highlight advantages, disadvantages, surgical outcomes, and describe an improved endoscopic transoral technique. Methods A systematic review of peer‐reviewed articles was conducted on November 11, 2025 in PubMed, Embase, the Cochrane Library, and Medline.
Nana‐Hawwa Abdul‐Rahman   +4 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Effects of auricular vagus nerve stimulation on brain activity, cognitive parameters and well-being

open access: green, 2017
Thomas Polak   +4 more
openalex   +2 more sources

Children and adolescents with disorders of gut–brain interaction with comorbid hypermobility and orthostatic intolerance have worse outcomes

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Disorders of gut–brain interaction (DGBI) affect about 40% of children and are often comorbid with hypermobility spectrum disorders (HSDs) and orthostatic intolerance (OI). However, how these comorbidities impact outcomes in pediatric DGBI is not well understood.
Neha Santucci   +6 more
wiley   +1 more source

Factors Affecting Outcomes in Anterior Cervical Spine Surgery

open access: yesThe Laryngoscope, EarlyView.
This retrospective cohort study examined perioperative complications after anterior cervical spine surgery (ACSS) in 3401 patients treated at a tertiary academic institution. Otolaryngologist co‐surgeons in revision and upper cervical spine (C1‐4) cases, and high‐volume spine surgeons (≥ 15 annual cases) were associated with lower complication rates ...
Nana‐Hawwa Abdul‐Rahman   +5 more
wiley   +1 more source

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