Results 11 to 20 of about 771,705 (359)

Vagus nerve stimulation and inflammation: expanding the scope beyond cytokines

Bioelectronic Medicine, 2022
Approximately 20 years ago it was discovered that the vagus nerve regulates pro-inflammatory cytokine levels and inflammation. Subsequent research using several preclinical models revealed that vagus nerve stimulation evokes a protective decrease in pro ...
Aidan Falvey
doaj   +2 more sources

α-Synuclein induces prodromal symptoms of Parkinson’s disease via activating TLR2/MyD88/NF-κB pathway in Schwann cells of vagus nerve in a rat model

Journal of Neuroinflammation, 2023
Background Increasing evidence suggests that patients with Parkinson's disease (PD) present with peripheral autonomic dysfunction (AutD) that even precedes motor deficits, through which α-synuclein can spread to the central nervous system.
Yue Cheng, Qing Tong, Yongsheng Yuan, Xinna Song, Wenwen Jiang, Yueping Wang, Wenjie Li, Yangxia Li, Kezhong Zhang   +8 more
doaj   +2 more sources

Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes

Acta Diabetologica, 2023
Aims The purpose of this review is to explore the interconnected pathways of the microbiota-gut-brain axis (MGBA), focusing on the roles of the vagus nerve and glucagon like peptide-1 in appetite control, and in the development of obesity and diabetes ...
Susanna Longo, S. Rizza, M. Federici
semanticscholar   +1 more source

Role of Vagus Nerve Stimulation in the Treatment of Chronic Pain

Neuroimmunomodulation, 2023
Vagus nerve stimulation (VNS) can modulate vagal activity and neuro-immune communication. Human and animal studies have provided growing evidence that VNS can produce analgesic effects in addition to alleviating refractory epilepsy and depression.
Peiqi Shao, Huili Li, Jia Jiang, Y. Guan, Xueming Chen, Yun Wang   +5 more
semanticscholar   +1 more source

Neuroimmunomodulation of vagus nerve stimulation and the therapeutic implications

Frontiers in Aging Neuroscience, 2023
Vagus nerve stimulation (VNS) is a technology that provides electrical stimulation to the cervical vagus nerve and can be applied in the treatment of a wide variety of neuropsychiatric and systemic diseases.
Yi-Ting Fang, Ye-Ting Lin, Wu-Lung Tseng, P. Tseng, G. Hua, Y. Chao, Yi-Jen Wu   +6 more
semanticscholar   +1 more source

Vagus nerve inflammation contributes to dysautonomia in COVID-19

Acta Neuropathologica, 2023
Dysautonomia has substantially impacted acute COVID-19 severity as well as symptom burden after recovery from COVID-19 (long COVID), yet the underlying causes remain unknown.
Marcel S. Woo, M. Shafiq, A. Fitzek, M. Dottermusch, H. Altmeppen, B. Mohammadi, Christina Mayer, L. Bal, Lukas Raich, J. Matschke, S. Krasemann, S. Pfefferle, T. Brehm, M. Lütgehetmann, Julia Schädler, M. Addo, J. Schulze zur Wiesch, B. Ondruschka, M. Friese, M. Glatzel   +19 more
semanticscholar   +1 more source

Neuroimmune Modulation Through Vagus Nerve Stimulation Reduces Inflammatory Activity in Crohn’s Disease Patients: A Prospective Open-label Study

Journal of Crohn's & Colitis, 2023
Background and Aims Crohn’s disease [CD] is a debilitating, inflammatory condition affecting the gastrointestinal tract. There is no cure and sustained clinical and endoscopic remission is achieved by fewer than half of patients with current therapies ...
Geert R. D’Haens, M. Eberhardson, Ž. Čabrijan, S. Danese, Remco van den Berg, M. Löwenberg, G. Fiorino, P. Schuurman, Göran Lind, Per Almqvist, P. Olofsson, Kevin J Tracey, Stephen B Hanauer, Ralph Zitnik, D. Chernoff, Y. Levine, Prof. Geert D’Haens   +16 more
semanticscholar   +1 more source

International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020)

Frontiers in Human Neuroscience, 2021
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation (tVNS) across basic, translational and clinical research.
A. Farmer, A. Strzelczyk, A. Finisguerra, A. Gourine, A. Gharabaghi, A. Hasan, A. Burger, Andrés M. Jaramillo, A. Mertens, A. Majid, B. Verkuil, B. Badran, C. Ventura-Bort, C. Gaul, C. Beste, Christopher M. Warren, D. Quintana, D. Hämmerer, E. Freri, E. Frangos, E. Tobaldini, E. Kaniušas, F. Rosenow, F. Capone, F. Panetsos, G. Ackland, G. Kaithwas, Georgia H. O’Leary, Hannah Genheimer, H. Jacobs, I. Van Diest, J. Schoenen, J. Redgrave, J. Fang, J. Deuchars, J. Szeles, J. Thayer, Kaushik More, K. Vonck, L. Steenbergen, L. Vianna, L. McTeague, M. Ludwig, M. Veldhuizen, M. De Couck, M. Casazza, M. Keute, M. Bikson, M. Andreatta, Martina D’Agostini, M. Weymar, M. Betts, Matthias Prigge, M. Kaess, M. Roden, M. Thai, Nathaniel M. Schuster, N. Montano, Niels Hansen, N. Kroemer, P. Rong, Rico Fischer, R. Howland, R. Sclocco, R. Sellaro, Ronald G. García, S. Bauer, S. Gancheva, Stavros Stavrakis, S. Kampusch, S. Deuchars, S. Wehner, S. Laborde, T. Usichenko, T. Polak, T. Zaehle, U. Borges, V. Teckentrup, V. Jandackova, V. Napadow, J. Koenig   +80 more
semanticscholar   +1 more source

Vagus Nerve and Underlying Impact on the Gut Microbiota-Brain Axis in Behavior and Neurodegenerative Diseases

Journal of Inflammation Research, 2022
The gut microbiota is the most abundant and diverse microbiota in the human body and the vagus nerve is the most widely distributed and complex nerve in the body, both of them are essential in maintaining homeostasis. The most important phenomenon is how
Yi-Min Han, Bo-ya Wang, Han Gao, Chengwei He, Rongxuan Hua, Chen Liang, Sitian Zhang, Ying Wang, Shuzi Xin, Jing-dong Xu   +9 more
semanticscholar   +1 more source

Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

Frontiers in Neurology, 2022
Depression is a worldwide disease causing severe disability, morbidity, and mortality. Despite abundant studies, the precise mechanisms underlying the pathophysiology of depression remain elusive.
Chaoren Tan, Qiqi Yan, Yue Ma, J. Fang, Yongsheng Yang   +4 more
semanticscholar   +1 more source