Results 141 to 150 of about 197,837 (340)

Vagal nerve stimulation therapy: what is being stimulated? [PDF]

, 2014
Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In
Ardell, Jeffrey L, Armour, John A, Kember, Guy, Zamir, Mair   +3 more
core   +3 more sources

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

Intraoperative Neurophysiological Monitoring for Endoscopic Endonasal Approaches to the Skull Base: A Technical Guide. [PDF]

, 2016
Intraoperative neurophysiological monitoring during endoscopic, endonasal approaches to the skull base is both feasible and safe. Numerous reports have recently emerged from the literature evaluating the efficacy of different neuromonitoring tests during
Doan, Adam T., Evans, James J., Kenning, Tyler J., Lober, Robert M., Matsumoto, Craig I., Singh, Harminder, Vogel, Richard W.   +6 more
core   +3 more sources

Executive dysfunction and employment in epilepsy

Epilepsia, EarlyView.
Abstract Objective Executive dysfunction, affective symptoms, and unemployment are prevalent in patients with epilepsy, yet the relation between these variables remains poorly understood. The present study examined: (1) The relationship between epilepsy‐related variables, affective symptoms, and executive functions (EFs); and (2) how these variables ...
Lisa E. Hauger, Christoph Helmstaedter, Morten I. Lossius, Kristin Å. Alfstad, Ellen Molteberg, Halvor Torgersen, Annette H. Skogan   +6 more
wiley   +1 more source

Vagus nerve stimulation for epilepsy

Rinsho Shinkeigaku, 2011
Vagus nerve stimulation is the first electrical stimulation therapy for epilepsy. While its clinical use was approved by the European Union in 1994 and by the United States in 1997, it was approved last year and coverage by public insurance started last July in Japan.
Kensuke, Kawai, Kenichi, Usami, Nobuhito, Saito   +2 more
openaire   +3 more sources

Agreement and 2‐year trajectories of youth‐ and parent‐reported health‐related quality of life in youth with epilepsy treated with surgery vs medical therapy

Epilepsia, EarlyView.
Abstract Objective This cohort study examined the agreement between youth‐ and parent‐reported health‐related quality of life (HRQOL) of children treated with epilepsy surgery compared to medical therapy. A second aim was to evaluate whether changes in HRQOL over 2 years differed between the two groups, and to determine whether these trajectories ...
Mary Lou Smith, Klajdi Puka, Elysa Widjaja   +2 more
wiley   +1 more source

Vagus Nerve Stimulation for Seizures

Archives of Medical Research, 2000
It is agreed that 1% of the general population is afflicted with epilepsy and close to 30% of epilepsy patients are intractable to medications. In spite of a recent increase in the number of new medications that are available on the market, many patients continue to have seizures or their seizures are controlled at the expense of intolerable side ...
Department of Neurology and Neuroscience, University of Florida, and College of Medicine and Malcolm Randall Veterans Administration Medical Center (VAMC), Gainesville, FL, USA ( host institution ), Uthman, Basim M   +1 more
openaire   +3 more sources

Schwannoma of the cervical vagus nerve: A rare benign neurogenic tumor [PDF]

, 2013
A schwannoma, also known as an acoustic neuroma, is a benign nerve sheath tumor composed of schwann cells, which normally produce the insulating myelin sheath covering the peripheral nerves.
AKIN, Istemihan, ARIKOK, Ataturker, GUNSOY, Behcet, SAHAN, Mehmet, SIMSEK, Gokce   +4 more
core   +1 more source

Deep brain stimulation of the thalamus for intractable epilepsy (FRANCE study): A randomized clinical trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès, Fabrice Bartolomei, Anca Nica, Claire Haegelen, Lorella Minotti, Brigitte Piallat, Chrystele Mosca, Sandrine Massicot, Sylvain Rheims, Marc Guenot, Emmanuel Cuny, Jérome Aupy, Louis Maillard, Sophie Colnat‐Coulbois, Corentin Leroy, Romain Carron, Philippe Coubes, Philippe Gélisse, Carine Karachi, Vincent Navarro, Bertrand Devaux, Francine Chassoux, Phlippe Derambure, Nicolas Reyns, Jean Christope Sol, Luc Valton, Denys Fontaine, Veronique Bourg, Philippe Kahane, Sandra David‐Tchouda, Jean Regis   +30 more
wiley   +1 more source

Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats

Journal of Neuroinflammation, 2012
Background In sepsis syndromes the severity of the inflammation triggers microvascular dysfunction and early organ failure. We studied the effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculatory integrity in an endotoxinemic
Mihaylova Stanka, Killian Anke, Mayer Konstantin, Pullamsetti Soni, Schermuly Ralph, Rosengarten Bernhard   +5 more
doaj   +1 more source