Cholecystokinin: Clinical aspects of the new biology
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
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Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth+5 more
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Use of laryngeal muscle evoked potential recording for experimental vagus nerve stimulation. [PDF]
Bachmann H, Raedt R, Laureys G, Vonck K.
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A perspective on automated rapid eye movement sleep assessment
Summary Rapid eye movement sleep is associated with distinct changes in various biomedical signals that can be easily captured during sleep, lending themselves to automated sleep staging using machine learning systems. Here, we provide a perspective on the critical characteristics of biomedical signals associated with rapid eye movement sleep and how ...
Mathias Baumert, Huy Phan
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Successful application of vagus nerve stimulation in super refractory status epilepticus associated with MERRF syndrome. [PDF]
Baysal L+4 more
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Dreaming in patients with epilepsy: a cross‐sectional cohort study
Dream recall frequency in patients with epilepsy is modulated by determinants shared with healthy subjects (age, nocturnal awakenings, role of the parieto‐occipital region) and by epilepsy‐related factors (seizure frequency, epileptic focus location).
Maïlis Charpentier‐Hélary+11 more
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Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization. [PDF]
Wen J+10 more
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Ikelos‐Rating Scale: Validation of a Behavioural Severity Marker in REM Sleep Behaviour Disorder
ABSTRACT The Ikelos‐Rating Scale (Ikelos‐RS) is a new, expert‐interviewed and bedpartner‐reported severity marker assessing frequency and expression of isolated REM sleep behaviour disorder (iRBD), a precursor of clinical α‐synucleinopathies. This study aimed to validate the Ikelos‐RS in 180 patients with three‐night PSG‐confirmed iRBD (68.4 ± 8.3 ...
Sophia Stotz, Frederik Bes, Dieter Kunz
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Assessing the therapeutic potential of vagus nerve stimulation in autoimmune diseases: A systematic review. [PDF]
Chan E, Mani AR.
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The Future of Non‐Invasive Brain Stimulation in Sleep Medicine
ABSTRACT Non‐invasive brain stimulation (NIBS) methods carry particular appeal as non‐pharmacological approaches to inducing or improving sleep. However, intense research efforts to use transcranial magnetic stimulation (TMS) and electrical stimulation (tES) for sleep modulation have not yet delivered evidence‐based NIBS treatments in sleep medicine ...
Lukas B. Krone+3 more
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