Results 191 to 200 of about 86,827 (306)

Extracellular Vesicles in Osteoarthritis: From Pathogenic Mediators to Engineered Therapeutics in a Precision Medicine Roadmap

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach   +2 more
wiley   +1 more source

Radiographic and Clinical Outcomes of Intermetatarsal Screw Fixation in First Tarsometatarsal Arthrodesis for Hallux Valgus

open access: gold
Ashley N. Kimbel   +4 more
openalex   +1 more source

The Viladot-Regnauld operation for hallux valgus [PDF]

open access: bronze, 2003
G Monteleone   +3 more
openalex   +1 more source

Comparable outcomes and early revision rates between restricted and unrestricted functional knee positioning in robotic‐assisted total knee arthroplasty for varus deformities ≥10°

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1682-1690, May 2026.
Abstract Purpose Functional knee positioning (FKPos) in total knee arthroplasty (TKA) optimises outcomes by balancing individual anatomical and soft tissue characteristics. Managing marked varus deformity presents challenges in achieving balance when tibial alignment is restricted to 3° of varus, necessitating either medial soft tissue release or ...
Christos Koutserimpas   +6 more
wiley   +1 more source

Performance of Distal and Proximal First Metatarsal Osteotomy in Hallux Valgus Surgery: A Systematic Review and Meta-Analysis. [PDF]

open access: yesOrthop Rev (Pavia)
Harahap R   +6 more
europepmc   +1 more source

Unrestricted kinematic alignment in varus total knee arthroplasty outperforms mechanical alignment in CPAK I phenotype, but yields comparable outcomes in CPAK IV: A retrospective analysis from the FP‐UCBM Knee Study Group

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1759-1765, May 2026.
Abstract Purpose To compare clinical outcomes in varus‐aligned patients undergoing cruciate‐retaining total knee arthroplasty (TKA) with mechanical alignment (MA) versus unrestricted kinematic alignment (KA). The hypothesis was that KA would yield superior outcomes, and that preserving joint line obliquity—regardless of alignment technique—would be ...
Edoardo Franceschetti   +9 more
wiley   +1 more source

Progression of bone and joint space deformity in patients with mild knee osteoarthritis: Data from the IMI-APPROACH cohort. [PDF]

open access: yesOsteoarthr Cartil Open
Nguyen HC   +17 more
europepmc   +1 more source

Personalized alignment in total knee arthroplasty reduces patellar tilt: A retrospective study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1766-1775, May 2026.
Abstract Purpose Patellofemoral kinematics is crucial for patient satisfaction following total knee arthroplasty (TKA). A postoperative patellar tilt greater than 5° has been associated with inferior clinical outcomes. While a femoral component external rotation beyond 3° is generally protective against patellar tilt, personalized alignment may not ...
Alexandre Le Guen   +4 more
wiley   +1 more source

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