Results 181 to 190 of about 6,125,000 (281)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Description and validation of the ice-sheet model Yelmo (version 1.0)

, 2019
Alexander Robinson, Jorge Álvarez-Solas, Marisa Montoya, Heiko Goelzer, Ralf Greve, Catherine Ritz   +5 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Development and Validation of a Nomogram Incorporating Nutritional and Lipid Metabolism Indices to Predict Survival in Non-Small Cell Lung Cancer Patients with Malignant Pleural Effusion. [PDF]

Cancer Manag Res
Chen B, Yang L, Shen K, Gao W.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Development and validation of a clinico-biological score for Brucella spondylitis: a two-center study. [PDF]

BMC Infect Dis
Pan S, Chen S, Zhou K, Wu J, Wu C, Tuerxun M, Chong Y, Zhu J.   +7 more
europepmc   +1 more source

Identification and Validation of Evolutionarily Conserved Unusually Short Pre-mRNA Introns in the Human Genome [PDF]

, 2015
Makoto Shimada, Noriko Sasaki-Haraguchi, Akila Mayeda   +2 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

An exploratory study on predicting HER2-positive expression status of breast cancer using ultrasound radiomics combined with machine learning models. [PDF]

PLoS One
Zhang XR, Yuan SS, Hu JJ, Chen QQ, Xiao YJ, Huang YF, Yu XQ, Lu F, Shen Y, Fu XH.   +9 more
europepmc   +1 more source

Validation of a 4-item child perception questionnaire in Australian children

, 2020
Xiangqun Ju, Pedro Henrique Ribeiro Santiago, Loc Do, Lisa Jamieson   +3 more
openalex   +2 more sources