Results 221 to 230 of about 6,428,897 (326)

Glinternet cross-validation error over the lambda index.

Thomas Le Menestrel (22755945), Erin Craig (22755948), Robert Tibshirani (196), Trevor Hastie (195), Manuel Rivas (268944)   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

CT-based deep learning signatures associated with transcriptomic heterogeneity and combined with nutritional biomarkers improve prediction of 3-year overall survival in esophageal squamous cell carcinoma. [PDF]

Insights Imaging
Jia J, Cheng Y, Wang J, Bai G, Han L, Xu L, Niu Y.   +6 more
europepmc   +1 more source

Calibration plots for random forest applied to accelerometer data under three approaches (NR, PCA, fFPCA) and two cross validation methods (n-fold and farm-fold).

Muhammad Usman Riaz (21615573), Luke O’Grady (3774166), Conor G. McAloon (10712896), Finnian Logan (21615576), Isobel Claire Gormley (11599588)   +4 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

5-fold cross-validation performance of the proposed CILAD-Net model on the Metadata (IoT) dataset.

Ritika Ritika (10667302), Rajender Singh Chhillar (22453795), Sandeep Dalal (22453798), Surjeet Dalal (4906894), Iyyappan Moorthi (22453801), Mitiku Dubale (12506099), Arshad Hashmi (13835488)   +6 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Noah-Agent: A Multi-Expert AI Agent Framework for Automated Parameterization and Validation of Large-Scale Fortran Climate Models

Wu, Koutian
openalex   +1 more source