Results 241 to 250 of about 6,428,897 (326)

Engineering of an advanced automated Biomechatronics Solution and biomedical Validation in single Muscle Cells and Micro-Tissues from a rodent Model of Human inherited Desminopathy

Charlotte Malena Pollmann
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Interpretable Machine Learning for Survival Prediction in Small Cell Lung Cancer Patients With Brain Metastases: A Population-Based Study With External Validation. [PDF]

Cancer Control
Luo N, Tan S, Li X, Liu S, Xie S, Huang X, Wu D.   +6 more
europepmc   +1 more source

Empirical Validation of Momentum-Induced Spacetime Compression: A Comprehensive Analysis of 124 SPARC Galaxies Testing MIND-CM vs ΛCDM

Alvaro Fabian BRICIO ARZUBIDE
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Validation and prognostic impact of ambulatory screening for sleep disordered breathing in patients with chronic systolic heart failure

, 2013
Zavaglia, Pier Paolo
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Performance of Artificial Intelligence Models in Radiographic Image Analysis for Predicting Hip and Knee Prosthesis Failure: A Systematic Review. [PDF]

Bioengineering (Basel)
Stuani R, Di Maio M, Di Matteo V, Chiappetta K, Grappiolo G, Loppini M.   +5 more
europepmc   +1 more source

Designing and validating the study on the influence of social media influencers scale [PDF]

Wu, Jiayu, Mohd Mothar, Noor Mayudia, Ali, Anuar   +2 more
openalex