Results 241 to 250 of about 6,125,000 (281)

Artificial intelligence-assisted diagnosis of glomerular nephritis using a pathological image analysis approach: a multicentre model development and validation study. [PDF]

EClinicalMedicine
Nie S, Jia N, Chen H, Chen R, Geng J, Shao X, Zhou S, Liu J, Jin L, Sun Y, Luo F, Pang M, Wang G, Zhang Q, Hou FF.   +14 more
europepmc   +1 more source

Imperial strategy of cancer cells through mitochondrial transfer

Molecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

Recommendations for Validating Omics Prediction Models: Insights from a Lung Cancer RNA Biomarker Study. [PDF]

Cancer Epidemiol Biomarkers Prev
Pestarino L, Fortner RT, Nøst TH, Fotopoulos I, Urbarova I, Røe OD, Langseth H, Rounge TB.   +7 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Computer intelligence based model for mental health detection among Indian farming communities. [PDF]

Sci Rep
Agarwal J, Sharma S, Madan P, Vishnoi A, Narooka P.   +4 more
europepmc   +1 more source

Validating Brain Tumor Reporting and Data System (BT-RADS) as a Diagnostic Tool for Glioma Follow-Up after Surgery [PDF]

Yassir Edrees Almalki, Mohammad Abd Alkhalik Basha, Maha Ibrahim Metwally, Nesma Adel Zeed, Mohamad Gamal Nada, Sharifa Khalid Alduraibi, Ahmed A. Morsy, Rawda Balata, Ahmed Z. Al Attar, Mona G. Amer, Mohammed Farag, Sameh Abdelaziz Aly, Ahmed M. Abdelkhalik Basha, Enas Mahmoud Hamed   +13 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A lightweight CNN for colon cancer tissue classification and visualization. [PDF]

Front Oncol
Li J, Goh W, Jhanjhi NZ.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source