Results 261 to 270 of about 8,300,854 (416)

Proposed use of the plenary powers to suppress the generic names Prothechus Rondani, 1856, and Alloneura Rondani, 1856, for the purpose of validating the generic names Verrallia Mik, 1899, and Tomosvaryella Aczél, 1939 (Class Insecta, Order Diptera)

, 1958
D. Elmo Hardy
openalex   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Overexpression of the GmERF071 gene confers resistance to soybean cyst nematode in soybean. [PDF]

Plant Genome
Xiong E, Xu J, Feng P, Lian Y, Zhi X, Li K, Zhang E, Li B, Zhao S, Liu C, Wei C, Li P, Zhao Y, Zhao L, Zheng M, Zhang H, Li Y, Chu S, Jiao Y.   +18 more
europepmc   +1 more source

Proposed use of the plenary powers to validate and protect the family-group name "Mayaitidae" Spath (L. F.), 1928 (Class Cephalopoda, Order Ammonoidea)

, 1955
W. J. Arkell
openalex   +2 more sources

Validation redefined

Toxicology in Vitro, 2018
Piersma, Aldert H, van Benthem, Jan, Ezendam, Janine, Kienhuis, Anne S   +3 more
openaire   +5 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

A methodological systematic review of validation and performance of sepsis real-time prediction models. [PDF]

NPJ Digit Med
Wang Z, Wang W, Sun C, Li J, Xie S, Xu J, Zou K, Jin Y, Yan S, Liao X, Kang Y, Coopersmith CM, Sun X.   +12 more
europepmc   +1 more source

Validation of Defectively Executed Wills by Holographic Testamentary Instrument: Integration and Incorporation by Reference

, 1956

openalex   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Emerging artificial intelligence-driven precision therapies in tumor drug resistance: recent advances, opportunities, and challenges. [PDF]

Mol Cancer
Mao Y, Shangguan D, Huang Q, Xiao L, Cao D, Zhou H, Wang YK.   +6 more
europepmc   +1 more source