Results 311 to 320 of about 8,300,854 (416)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

The novel CKD-INF score for distinguishing infectious from non-infectious inflammation in patients with non-dialysis chronic kidney disease. [PDF]

Sci Rep
Beberashvili I, Shaheen K, Nizri E, Stav K, Efrati S.   +4 more
europepmc   +1 more source

Opinion 438 Validation under the Plenary Powers of the generic name Rhinopteraspis Jaekel, 1919 (class Ostracodermi)

, 1957
Francis Hemming
openalex   +2 more sources

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

The NERVE-ML (neural engineering reproducibility and validity essentials for machine learning) checklist: ensuring machine learning advances neural engineering^. [PDF]

J Neural Eng
Carlson DE, Chavarriaga R, Liu Y, Lotte F, Lu BL.   +4 more
europepmc   +1 more source

Opinion 369 Suppression Under the Plenary Powers of the Generic Names Tylos Meigen 1800 (Class Insecta, Order Diptera) and Tylos Heyden 1826 (Class Arachnida) and Validation Thereby of the Generic Names Tylos Audouin, (1826) (Class Crustacea, Order Isopoda) and Micropeza Meigen 1803 (Class Insecta Order Diptera)

, 1955
Francis Hemming
openalex   +2 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Development and validation of machine learning models for predicting low muscle mass in patients with obesity and diabetes. [PDF]

Lipids Health Dis
Ge J, Sun S, Zeng J, Jing Y, Ma H, Qian C, Cui R, Qu S, Sheng H.   +8 more
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source