Results 51 to 60 of about 58,285,719 (241)

Topic and focus : two structural positions associated with logical functionsin the left periphery of the Hungarian sentence [PDF]

open access: yes, 2008
The paper explicates the notions of topic, contrastive topic, and focus as used in the analysis of Hungarian. Based on distributional criteria, topic and focus are claimed to represent distinct structural positions in the left periphery of the Hungarian ...
Kiss, Katalin   +2 more
core   +1 more source

Development and Psychometric Evaluation of the Scale Measuring the Preparation of Emergency Nurses in the Care of Trauma Patients [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: The level of preparation of nurses in performing correct, timely, and appropriate actions plays an important role in saving trauma patients. Examining the level of preparation of nurses requires a valid and specific tool.
Mohammad Abbasinia   +6 more
doaj  

Psychometric analysis of ProQOL-BR in nursing: building hospital safety and protection [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to analyze the psychometric properties of the ProQOL-BR instrument in hospital nursing professionals. Methods: a methodological study to validate the ProQOL-BR. Confirmatory factor analysis, assessment of local and global adjustment quality,
Frederico Marques Andrade   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Women's Studies and Its Institutionalization as an Interdisciplinary Field: Past, Present, and Future

open access: yes, 2023
To celebrate the fiftieth anniversary of WSQ, this article offers a snapshot of the history of women’s studies (WS), one that establishes it as an interdisciplinary field alongside Black studies and ethnic studies.
Saraswati, L. Ayu, Shaw, Barbara L.
core   +1 more source

Reliability and Validity of a Chinese Version of Urinary Tract Infection Symptom Assessment Questionnaire

open access: yesInternational Brazilian Journal of Urology, 2015
Objectives:Our study evaluates the reliability and validity of a Chinese version of the Urinary Tract Infection Symptom Assessment questionnaire (UTISA).Material and Methods:Our study enrolled women who were diagnosed with uncomplicated urinary tract ...
Shang-Jen Chang   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Bridging the AI chasm in oncology: a standardized platform to enable the in silico clinical validation of AI models within the CHAIMELEON Project

open access: yesEuropean Radiology Experimental
Objective Artificial intelligence (AI) shows promise for improving cancer management, but clinical adoption is limited by the absence of standardized validation tools.
Adrian Galiana-Bordera   +9 more
doaj   +1 more source

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