Results 151 to 160 of about 4,984,553 (349)

Supplementary Figure 2 from Recommendations for Validating Omics Prediction Models: Insights from a Lung Cancer RNA Biomarker Study [PDF]

Luca Pestarino, Renée T. Fortner, Therese Haugdahl Nøst, Ioannis Fotopoulos, Ilona Urbárová, Oluf Dimitri Røe, Hilde Langseth, Trine B. Rounge   +7 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Food Composition Table-Based Estimation of Energy and Major Nutrient Intake in Comparison with Chemical Analysis: A Validation Study in Korea

, 2003
Eul-Sang Kim, Yang‐Sook Ko, Jung-Hun Kim, Naoko Matsuda‐Inoguchi, Haruo Nakatsuka, Takao Watanabe, Shinichiro Shimbo, Masayuki Ikeda   +7 more
openalex   +2 more sources

Measuring competence: Validating a new Pelvic Assessment Tool (The PEAT Study) [PDF]

, 2016
Aisha Janjua, Justin Chu, Smith Paul, T. Justin Clark   +3 more
openalex   +1 more source

PENGEMBANGAN LKPD INTERAKTIF BERBASIS LIVEWORKSHEET MATERI SUMBER DAYA ALAM IPAS KELAS IV SEKOLAH DASAR [PDF]

Observations and interviews with fourth-grade instructors at SD Negeri Sungkai 1, Kab. Banjar, revealed that they continued to use the school's conventional LKPDs and textbooks during IPAS lessons.
Bagastama, Muhammad Naufal
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Study validity

The Journal of Indian Prosthodontic Society, 2018
openaire   +3 more sources

Establishing Fully-Automated Fundus-Controlled Dark Adaptometry: A Validation and Retest-Reliability Study [PDF]

, 2023
Jeannine Oertli, Kristina Pfau, Hendrik P. N. Scholl, Brett G. Jeffrey, Maximilian Pfau   +4 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Development and validation of a prognostic nomogram for bone metastasis from lung cancer: A large population-based study [PDF]

, 2022
Weihua Li, Zixiang Guo, Zehui Zou, Momen Alswadeh, Heng Wang, Xuqiang Liu, Xiaofeng Li   +6 more
openalex   +1 more source