Results 161 to 170 of about 4,984,553 (349)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Neither Donor nor Recipient Mitochondrial Haplotypes Are Associated with Unrelated Donor Transplant Outcomes: A Validation Study from the CIBMTR

, 2021
Logan G. Spector, Stephen R. Spellman, Bharat Thyagarajan, Kenneth B. Beckman, Cody Hoffmann, John Garbe, Theresa Hahn, Lara E. Sucheston‐Campbell, Michaela Richardson, Todd E De For, Jakub Tolar, Michael R. Verneris   +11 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

ADNEX risk prediction model for diagnosis of ovarian cancer: systematic review and meta-analysis of external validation studies [PDF]

Lasai Barreñada, Ashleigh Ledger, Paula Dhiman, Gary S. Collins, Laure Wynants, Jan Y. Verbakel, D. Timmerman, L. Valentin, Ben Van Calster   +8 more
openalex   +1 more source

Improving Pelvic Floor Muscle Training Adherence Among Pregnant Women: Validation Study (Preprint)

, 2021
Aida Jaffar, Sherina Mohd Sidik, Chai Nien Foo, Novia Admodisastro, Sobihatun Nur Abdul Salam, Noor Diana Ismail   +5 more
openalex   +1 more source

Pictograms for safer medication handling by health care workers: a validation study in nursing students in Poland [PDF]

, 2022
Piotr Merks, Régis Vaillancourt, Damien Roux, Rafał Gierczyński, Grzegorz Juszczyk, Katarzyna Plagens-Rotman, Urszula Religioni, Jameason D. Cameron, Mike Zender   +8 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A Single-Arm, Multicenter Validation Study of Prostate Cancer Localization and Aggressiveness With a Quantitative Multiparametric Magnetic Resonance Imaging Approach

, 2019
Marnix C. Maas, Geert Litjens, Alan J. Wright, Ulrike Attenberger, Masoom A. Haider, Thomas H. Helbich, Berthold Kiefer, Katarzyna J. Macura, Daniel Margolis, Anwar R. Padhani, Kirsten M. Selnæs, Geert Villeirs, Jurgen J. Fütterer, Tom W. J. Scheenen   +13 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

The Nurses' Innovative Behavior Inventory (NIBI): A development and validation study. [PDF]

PLoS One
Shahidi Delshad E, Soleimani M, Zareiyan A, Ghods AA.   +3 more
europepmc   +1 more source