Results 201 to 210 of about 2,566,277 (265)

Validation study of the antineutrophil cytoplasmic antibody (ANCA) kidney risk score in Japanese patients with ANCA-associated glomerulonephritis. [PDF]

Ren Fail
Yamashita A, Kitamura M, Muta K, Iwata M, Otsuka E, Torigoe K, Uchida T, Ichinose K, Takazono T, Sakamoto N, Kawakami A, Mukae H, Nishino T.   +12 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Improving Vancomycin Therapeutic Drug Monitoring With a Deep Learning-Based Two-Compartment Predictive Model: Development and Validation Study. [PDF]

JMIR AI
Mao B, Xie Z, Rasmy L, Nigo M, Zhi D.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Generalisable prediction models for outcomes after lumbar spinal stenosis surgery: a model development and external validation study. [PDF]

EClinicalMedicine
Berg B, Abbott A, Pedersen CF, Hedevik H, Gorosito MA, Joakimsen HL, Burman PJ, Mikalsen KØ, Andersen MØ, Ingebrigtsen T, Solberg T, Grotle M.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Multiphasic Evidential Decision-Making Matrix (MedMax) for Intrahepatic Cholangiocarcinoma: A Single-Center Validation Study. [PDF]

Cancers (Basel)
Ramouz A, Adeliansedehi A, Chagervand BM, Sabetkish N, Goeppert B, Springfeld C, Khajeh E, Mehrabi A, Majlesara A.   +8 more
europepmc   +1 more source

MRI Quantification of Liver Fibrosis Using Diamagnetic Susceptibility: An Ex Vivo Validation Study. [PDF]

Tomography
Li C, Zhang J, Dimov AV, Koehne de González AK, Prince MR, Li J, Romano D, Spincemaille P, Nguyen TD, Brittenham GM, Wang Y.   +10 more
europepmc   +1 more source

Reliability and Safety of Smartwatch Blood Pressure and Oxygen Saturation Measurements in Older Adults: Instrument Validation Study. [PDF]

JMIR Form Res
Madeira R, Esteves D, Neiva H, Maia A, Rondão C, Pinto N, Vercelli A, Pato MV.   +7 more
europepmc   +1 more source

Artificial Intelligence for Tumor Tissue Detection in Stomach Cancer: A Retrospective Algorithm Development and Validation Study. [PDF]

J Clin Med
Karnaukhov N, Palumbo VD, Voloshin M, Mongolin A, Skvortsov A, Karimov A, Gorbachev Y, Abramov K, Zabruntseva A, Yakubovsky G, Asaturova A, Palicelli A, Khomeriki S, Khatkov I.   +13 more
europepmc   +1 more source