A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Beyond reflection: using the clinician educator milestones in faculty development. [PDF]
Buck E, Monteiro FM, Turner K.
europepmc +1 more source
Closure to “Discussions of ‘Validity of Time-Compensated Temperature Parameters for Correlating Creep and Creep-Rupture Data’” (1956, Trans. ASME, 78, pp. 1429–1432) [PDF]
F. Garofalo, G. V. Smith, B. W. Royle
openalex +1 more source
Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee+3 more
wiley +1 more source
The assessment of psychometric properties of childbirth violence questionnaire in Iranian women. [PDF]
Jaafarpour M+5 more
europepmc +1 more source
Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani+2 more
wiley +1 more source
Validation of the Functional Activity Scoring Tool (FAST): a novel pictorial scale for assessing function in patients with knee osteoarthritis in primary care. [PDF]
Tang ZY+7 more
europepmc +1 more source
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez+5 more
wiley +1 more source
Development of an instrument for screening mental health based on Ayurvedic concept of Triguna. [PDF]
Ananda Lakshmy KN, Shajahan MA.
europepmc +1 more source