Results 81 to 90 of about 7,030,811 (353)

A comparison between different propagative schemes for the simulation of tapered step index slab waveguides [PDF]

, 1996
The performance and accuracy of a number of propagative algorithms are compared for the simulation of tapered high contrast step index slab waveguides.
Andrade, M. Adelaide, Baets, Roel, Bissessur, Hans K., Ctyroky, Jiri, Davies, J.B., Ducloux, E., Ettinger, Robert D., Gravert, M., Haes, Jan, Helfert, Stefan, Hoekstra, Hugo, Krijnen, Gijsbertus J.M., Leite, A., Nolting, H.P., Pregla, Reinholt, Ratovelomanana, F., Vodjdani, N., Weinert, C.M., Wijnands, F.H.G.M., Wijnands, F.H.G.M.   +19 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A New Internal Validity Index for Fuzzy c-Means Algorithm

IEEE Access
Fuzzy c-Means (FCM) is a popular clustering algorithm that can partition a set of objects into groups such that objects within a group are similar to each other and dissimilar to those in other groups.
Khairul Nurmazianna Ismail, Ali Seman, Khyrina Airin Fariza Abu Samah   +2 more
doaj   +1 more source

Instrumental Variables Estimation with Some Invalid Instruments and its Application to Mendelian Randomization

, 2014
Instrumental variables have been widely used for estimating the causal effect between exposure and outcome. Conventional estimation methods require complete knowledge about all the instruments' validity; a valid instrument must not have a direct effect ...
Cai, T. Tony, Kang, Hyunseung, Small, Dylan S., Zhang, Anru   +3 more
core   +2 more sources

The validity and reliability of the exposure index as a metric for estimating the radiation dose to the patient [PDF]

, 2020
Introduction With the introduction of digital radiography, the feedback between image quality and over-exposure has been partly lost which in some cases has led to a steady increase in dose.
A. England, Alzyoud, Butler, D. Browne, G. de Vries, H.G. Erenstein, J. Menzinga, J.A. Pires Jorge, M. Sauty, Ma, Mothiram, R.N. Higgins, R.S. Dwyer, Radiography, S. Curtin, S.F. Hommel, Seibert   +16 more
core   +5 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

An assessment of validity and responsiveness of generic measures of health-related quality of life in hearing impairment [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the ...
A Vuorialho, A Vuorialho, AK Cheng, AS Pickard, BG Bichey, CA Marra, CS Palmer, D Feeny, D Feeny, D Papaioannou, DL Streiner, DS Dalton, G Hawthorne, G Kobelt, GR Barton, GR Barton, GW Torrance, GWJA Damen, HY Lee, J Brazier, J Brazier, J Brazier, JE Brazier, JE Brazier, John Brazier, JPC Grutters, L Longworth, L Smith-Olinde, Louise Longworth, M Joore, MA Joore, MA Joore, MAB Joore, MKS Hol, P Dolan, PFM Krabbe, PK Sand, R Brooks, R Harper, RES Lovett, TH Sach, Y Yang, Yaling Yang   +42 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Refractive index of a transparent liquid measured with a concave mirror

, 2012
This paper describes the spherical concave mirror method for measuring the index of refraction of transparent liquids. We derived the refractive index equation using Snell's law and the small-angle approximation.
Amitabh Joshi, Blaker J W, Hecht E, Juan D Serna, Pedrotti F L, Rachna S, Wilson J D   +6 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source