Results 101 to 110 of about 17,377 (243)

Assessing the Impact of Twin Pregnancies on the Pelvic Floor Using 3-Dimensional Sonography A Pilot Study [PDF]

open access: yes, 2014
Objectives-The purpose of this study was to compare the morphologic characteristics of the pelvic floor musculature between women with twin and singleton pregnancies.Methods-We conducted a cross-sectional case-control study of 40 nulliparous women aged ...
Araujo Junior, Edward   +5 more
core   +3 more sources

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Effects of nocturnal periodic breathing on sympathetic nerve activity and ventilatory control at high altitude: a randomised, crossover study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche   +13 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

Spontaneous Otogenic Intracranial Pneumocephalus: A Case Report

open access: yesEar, Nose & Throat Journal
Spontaneous otogenic pneumocephalus (SOP) is a rare condition. We report a case of SOP that may be related to repeated Valsalva maneuvers. A young woman underwent repeated Valsalva maneuvers to restore Eustachian tube function and subsequently developed ...
Yuwan Song PhD   +5 more
doaj   +1 more source

Non‐epileptic paroxysmal events in Rett syndrome: A systematic review of case‐based and observational evidence

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 6, Page 746-754, June 2026.
This systematic review identifies and categorizes the spectrum of non‐epileptic paroxysmal events in Rett syndrome. Respiratory disturbances, behavioural episodes, and motor events were the most commonly reported. Improving clinician awareness and diagnostic clarity is key to avoiding unnecessary treatment and enhancing quality of life for individuals ...
Natasha Bhatti, Daniel E. Lumsden
wiley   +1 more source

Automated extraction of the plane of minimal hiatal dimensions and mid‐sagittal plane from 3D transperineal ultrasound

open access: yesMedical Physics, Volume 53, Issue 5, May 2026.
Abstract Background Transperineal ultrasound (TPUS) is a valuable imaging tool for evaluating patients with a variety of pelvic floor disorders, including pelvic organ prolapse (POP). Currently, calculating measurements of anatomical structures and relationships as well as extracting the mid‐sagittal (MS) plane of 2D and 3D ultrasound images are ...
Zachary Szentimrey   +5 more
wiley   +1 more source

Towards a Quantitative Understanding of Aficamten Clinical Pharmacology: Pharmacokinetic‐Cardiodynamic Modeling to Support Safety and Efficacy

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT In the phase 3 study SEQUOIA‐HCM (NCT05186818), aficamten, a next‐in‐class cardiac myosin inhibitor, was safe and efficacious in participants with obstructive hypertrophic cardiomyopathy (oHCM). Using pharmacokinetics/pharmacodynamics (PKPD) modeling, we quantified the relationship between aficamten exposure and cardiodynamic measures of ...
Justin D. Lutz   +5 more
wiley   +1 more source

Use and effectiveness of the Valsalva maneuver for supraventricular tachycardia in prehospital emergency care: a retrospective cohort study

open access: yesBMC Emergency Medicine
Background Vagal maneuvers are recommended as first-line therapy for hemodynamically stable supraventricular tachycardia (SVT). However, real-world data on their use in prehospital emergency medical services (EMS) remain limited.
Przemysław Żuratyński   +4 more
doaj   +1 more source

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