Background Patent foramen ovale (PFO) is a remnant of normal fetal anatomy and is present in approximately 25% of adults. PFO mainly causes right-to-left shunt (RLS). Clinical identification of RLS is crucial for certain patients, particularly those with
Lifei Tian +3 more
doaj +1 more source
Autonomic Influence on Heart Rate for Deep Breathing and Valsalva Maneuver in Healthy Subjects
Introduction: The Autonomic nervous system is responsible for regulation and integration of visceral functions. Disturbance of autonomic nervous system play crucial role in pathogenesis and clinical course of many diseases.
Reena Kumari Jha +2 more
doaj +1 more source
Effect of axillary brachial plexus blockade on baroreflex-induced skin vasomotor responses: Assessing the effectiveness of sympathetic blockade [PDF]
Background: The combination of laser Doppler flowmetry and non-invasive blood pressure monitoring allows the continuous observation of cutaneous vascular resistance (CVR).
Almond +41 more
core +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source
Background: The tegmen tympani and mastoideum are insidious locations of bony dehiscence. Large defects may result in encephalocele, cerebrospinal fluid leak, recurrent meningitis, and intracranial abscess.
Justin M. Soffer +3 more
doaj +1 more source
Multicompartmental prolapse: A comparative study between clinical examination and ultrasound
Abstract Objective The accurate diagnosis of multicompartment pelvic organ prolapse (POP) is fundamental to surgical success. This study aims to compare the diagnostic performance of transperineal ultrasound against clinical examination (pelvic organ prolapse quantification, POP‐Q) for the detection of compartmental defects in patients with ...
José Antonio García‐Mejido +5 more
wiley +1 more source
Pelvic venous disorders in women: Diagnosis and management for gynecologists
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni +5 more
wiley +1 more source
Autonomic modulation in patients with heart failure increases beat-to-beat variability of ventricular action potential duration [PDF]
Background: Exaggerated beat-to-beat variability of ventricular action potential duration (APD) is linked to arrhythmogenesis. Sympathetic stimulation has been shown to increase QT interval variability, but its effect on ventricular APD in humans has not
Behar, Jonathan +11 more
core +2 more sources
Phenotypic Subtypes of Obstructive Eustachian Tube Dysfunction as Defined by Cluster Analysis
Obstructive ETD encompasses five clinically distinct phenotypes, ranging from mild, post‐upper respiratory infection presentations to chronic, bilateral disease driven by sinusitis and reflux. These were identified through hierarchical cluster analysis of 490 patients using seven key clinical variables.
Jenilkumar H. Patel +4 more
wiley +1 more source
Transcranial doppler ultrasonography should it be the first choice for persistent foramen ovale screening? [PDF]
BACKGROUND: Persistent foramen ovale (PFO) is considered a cause of cryptogenic stroke and a risk factor for neurological events in young patients. The reference standard for identifying a PFO is contrast-enhanced transesophageal echocardiography (TEE ...
Anna Kabłak-Ziembicka +9 more
core +1 more source

