Results 101 to 110 of about 958,896 (366)
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Integration-Valuation Nexus in Invasive Species Policy [PDF]
This paper reviews recent work examining two topics of economic research vital for invasive species policy-integration and valuation. Integration requires bioeconomic models that blend invasive biology with economic circumstances and the feedback loops ...
Finnoff, David C.+3 more
core +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Conservative accounting and linear information valuation models [PDF]
Prior research using the residual income valuation model and linear information models has generally found that estimates of firm value are negatively biased.
Choi, Y S, O'Hanlon, J F, Pope, P F
core
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Let \(\tau\) (\({\mathcal A})\) denote the set of all convex transversals of a collection \({\mathcal A}\) of convex polytopes. Characterizations for finite \({\mathcal A}\), \({\mathcal B}\) with \(\tau\) (\({\mathcal A})=\tau ({\mathcal B})\) and also for \(\tau\) (\(\tau\) (\({\mathcal A}))=\tau ({\mathcal B})\) are established.
openaire +3 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Valuation of Slovene Publicly Traded Companies with a Valuation Model Based on Expected Earnings and Growth Opportunities [PDF]
The article sheds light on valuating Slovene publicly traded companies. The research aim is to solve the problems about company valuation in an emerging market, such as the Slovene market certainly is.
Igor Stubelj
core
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
In this paper we provide necessary and sufficient conditions for $ R=A\propto E $ to be a valuation ring where $E$ is a non-torsion or finitely generated $A-$module. Also, we investigate the $ (n,d) $ property of the valuation ring.
Mohammed Kabbour, Najib Mahdou
openaire +3 more sources