A framework for extending the health-related quality adjusted life year by combining instruments. [PDF]
Mulhern B+6 more
europepmc +1 more source
Discussion: “The Engineer as an Economist” and “Inventory Valuation of Machinery Plant” and “The Shop-Order System of Accounts” (Towne, Henry R., Smith, Oberlin, and Metcalfe, Henry, 1886, Trans. ASME, 7, pp. 428–468) [PDF]
W. E. Partridge+10 more
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Discussion: “On the Theory of the Finance of Lubrication, and on the Valuation of Lubricants by Consumers” (Thurston, Robert H., 1885, Trans. ASME, 6, pp. 437–460) and “On the Power Required to Overcome the Frictional Resistances of Engine and Shafting in Mills, and Its Cost” (Henthorn, John T., 1885, Trans. ASME, 6, pp. 461–472) [PDF]
Barrus+7 more
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Diabetic retinopathy detection based on mobile maxout network and weber local descriptor feature selection using retinal fundus image. [PDF]
Sheejakumari V+7 more
europepmc +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source