Results 61 to 70 of about 1,052,797 (378)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Simulation-based valuation of project finance: does model complexity really matter? [PDF]

open access: yes, 2010
This paper analyzes the impact of model complexity on the net present value distribution and the expected default probability of equity investments in project finance.
Kaserer, Christoph   +3 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Effect of Distance to Train Station and Mobile Coverage on Land Value: A Case of Tax Valuation in Oreamuno, Costa Rica

open access: yesBaltic Journal of Real Estate Economics and Construction Management, 2022
In Costa Rica, a land tax valuation model provided by the Technical Standardization Body (ONT) of the Ministry of Finance is used. This model considers homogeneous areas that include properties with similar characteristics and review factors that have ...
Molina Javier Paniagua   +3 more
doaj   +1 more source

Black-Scholes option valuation for scientific computing students [PDF]

open access: yes, 2004
Mathematical finance forms a modern, attractive source of examples and case studies for classes in scientific computation. I will show here how the Nobel Prize winning Black-Scholes option valuation theory can be used to motivate exercises in Monte Carlo
Higham, Desmond J.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

LIMITATIONS OF STOCK PRICE VALUATION BY CLASSICAL METHODS: CRITICS OF THEIR RELIABILITY AND INFLUENCE OF BEHAVIORAL FINANCE

open access: yesEkonomìčnij Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni "Kiïvsʹkij Polìtehnìčnij Institut", 2018
When trying to figure out which valuation method to use to value a stock for the first time, most investors will quickly discover the overwhelming number of valuation techniques available to them today.
Г. Мажара, А. Дрозд
doaj   +1 more source

Brownian excursions outside a corridor and two-sided Parisian options [PDF]

open access: yes, 2011
In this paper, we study the excursion time of a Brownian motion with drift outside a corridor by using a four states semi-Markov model. In mathematical finance, these results have an important application in the valuation of double barrier Parisian ...
Dassios, Angelos, Wu, Shanle
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Zakah on stocks: some unsettled issues [PDF]

open access: yes, 2002
Issues relating to zakah on equity shares are far from being settled if one considers the available fatawa and observed practices in many Muslim countries.
Islahi, Abdul Azim, Obaidullah, Mohammed
core  

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