Results 131 to 140 of about 12,817,234 (303)
LOGIT MODELS FOR POOLED CONTINGENT VALUATION AND CONTINGENT RATING AND RANKING DATA: VALUING BENEFITS FROM FOREST BIODIVERSITY CONSERVATION [PDF]
Contingent valuation and contingent rating and ranking methods for measuring willingness-to-pay for non-market goods are compared by using random coefficient models and data pooling methods.
Siikamaki, Juha, Layton, David F.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Deliberative Monetary Valuation (DMV) in Practice [PDF]
Economists concerned with validity, defined internally to the profession, are combining stated preference methods with participatory deliberation to address on-going criticism.
Clive L Spash
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Approximate value of the know-how of an institution of the regional innovation system in Antioquia
Civilizar, 2015 In regional innovation systems, the need has been sharpened to value intangible assets, especially the know how to negotiation and commercial transfer. Therefore, the aim of the article is to identify the main methods of valuing intangibles and deploy an
Carlos Eduardo Castaño Ríos +1 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Water Management and the Valuation of Indirect Environmental Services [PDF]
Comprehensive water basin and watershed planning and management require valuation of the intermediate ecological services provided to the water resources themselves.
James A Roumasset, Brooks Kaiser
core