Results 261 to 270 of about 262,960 (395)

Public hesitancy for AI-based detection of neurodegenerative diseases in France. [PDF]

Sci Rep
Rafaï I, Davin-Casalena B, Dubois D, Blayac T, Ventelou B.   +4 more
europepmc   +1 more source

The Valuation of a Dynamic Litigation Process: The Lawsuit as a (real) Option on an Option

Brian Grenadier, Steven R. Grenadier
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Elucidating attentional mechanisms underlying value normalization in human reinforcement learning

Cecchi R, Palminteri S, Gluth S.
europepmc   +1 more source

Cognitive effort devaluation and the salience network: a computational model of amotivation in depression. [PDF]

Front Psychiatry
Park IH, Lee CE, Jhung K.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Measuring and Valuing Health Using EuroQol Instruments: New Developments 2025 and Beyond. [PDF]

Appl Health Econ Health Policy
Devlin NJ, Xie F, Slaap B, Stolk E.
europepmc   +1 more source

A Real Options Approach to Amenity Valuation the Role of Uncertainty and Risk Aversion

, 2015
Andreas Mense
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Patient willingness to pay and preference for cervical cancer treatments among middle- and low-income populations in Xinjiang. [PDF]

J Patient Rep Outcomes
Zhu L, Wang Y, Yang S, Li Q, Wang J, Zhao J, Wang J, Wang Y.   +7 more
europepmc   +1 more source