Results 51 to 60 of about 249,987 (395)

Application of Real Options on the Decision-Making of Mining Investment Projects Using the System Dynamics Method

open access: yesIEEE Access, 2019
Estimating the valuation of mining projects has great significance for investment decision-making. Since the existing valuation methods are not appropriate for mining projects affected by various uncertainties over the long term, this paper presents a ...
Di Liu   +3 more
doaj   +1 more source

Numerical Valuation of American Basket Options via Partial Differential Complementarity Problems

open access: yesMathematics, 2021
We study the principal component analysis based approach introduced by Reisinger and Wittum (2007) and the comonotonic approach considered by Hanbali and Linders (2019) for the approximation of American basket option values via multidimensional partial ...
Karel J. in’t Hout, Jacob Snoeijer
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Valuation of Discrete Barrier American Options

open access: yesRevista Brasileira de Finanças, 2009
This article presents an approach and a model to valuing discrete barrier American options. The developed model consists of an adaptation of the method of Grant, Vora and Weeks (1997), in order to allow to incorporate the barriers. The Hybrid Quasi-Monte
Carlos Patrício Samanez   +1 more
doaj  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Optimal Investment under Cost Uncertainty

open access: yesRisks, 2018
This paper studies the valuation of real options when the cost of investment jumps at a random time. Three valuation formulas are derived. The first expresses the value of the project in terms of a collection of knockout barrier claims.
Jerome Detemple, Yerkin Kitapbayev
doaj   +1 more source

A Quasi-Closed-Form Solution for the Valuation of American Put Options

open access: yesInternational Journal of Financial Studies, 2020
This study develops a quasi-closed-form solution for the valuation of an American put option and the critical price of the underlying asset. This is an important area of research both because of a large number of transactions for American put options on ...
Cristina Viegas, José Azevedo-Pereira
doaj   +1 more source

Bet Option Valuation

open access: yes, 2023
https://ia904700.us.archive.org/33/items/local-vol-greek/LocalVolGreek ...
openaire   +1 more source

Real Options - Realistic Valuation [PDF]

open access: yesSSRN Electronic Journal, 2003
In valuation of real options, a widely accepted assumption is that the underlying real asset is perfectly correlated with a financial one. As a result, valuation techniques from the financial world can be used. Since this assumption is in general unrealistic and may lead to substantial mispricing, even if the correlation is very high but not perfect ...
Capiński, Marek, Patena, Wiktor
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

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