Results 121 to 130 of about 2,005,027 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Valuation Growth Analysis November 2003
Cover title.; "05/13/2004."; Report covers growth analysis from November 2002 to November ...
Kansas. Division of Property Valuation. Abstract Section.
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
On p-Adic Estimates of Weights in Abelian Codes over Galois Rings [PDF]
Let p be a prime. We prove various analogues and generalizations of McEliece's theorem on the p-divisibility of weights of words in cyclic codes over a finite field of characteristic p. Here we consider Abelian codes over various Galois rings.
Katz, Daniel Jerome
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
SMARANDACHE NON-ASSOCIATIVE RINGS [PDF]
An associative ring is just realized or built using reals or complex; finite or infinite by defining two binary operations on it. But on the contrary when we want to define or study or even introduce a non-associative ring we need two separate algebraic ...
Vasantha, Kandasamy
core +1 more source
Valuation Methods in Division Rings
Let \(R\) be a \(Z\)-filtered ring whose associated graded ring is an Ore domain. Then \(R\) can be embedded in a skew field. This was proved by the reviewer [Proc. Lond. Math. Soc., III. Ser. 11, 511-530 (1961; Zbl 0104.032)]. The author here gives another relatively short proof of this result; this brings the number of proofs in print to five [see ...
openaire +2 more sources
EXISTENTIAL ∅-DEFINABILITY OF HENSELIAN VALUATION RINGS [PDF]
AbstractIn [1], Anscombe and Koenigsmann give an existential ∅-definition of the ring of formal power series F[[t]] in its quotient field in the case where F is finite. We extend their method in several directions to give general definability results for henselian valued fields with finite or pseudo-algebraically closed residue fields.
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

