Results 181 to 190 of about 1,487,509 (274)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Evaluation of γ-Irradiation Effects on EPDM/SBS Blends for Durability and Recycling Potential. [PDF]

Polymers (Basel)
Zaharescu T, Bumbac M, Nicolescu CM, Stelescu MD, Borbath T, Borbath I.   +5 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Protein Design Enters the Artificial Intelligence Era: Foundations, Tools, and Emerging Paradigms. [PDF]

Comput Struct Biotechnol J
Mi Y, Shukla A, Tangney M, Tabirca S, Yallapragada VV.   +4 more
europepmc   +1 more source

ON GROUP REPRESENTATIONS OVER A VALUATION RING [PDF]

Proceedings of the National Academy of Sciences, 1961
openaire   +3 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Attenuated dietary motivation in Wilson's disease correlates with clinical severity. [PDF]

Orphanet J Rare Dis
Wang XQ, Wang YX, Ye ZH, Zhang ZL, Pan X, Wang XC, Cen SF.   +6 more
europepmc   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

Sustainable ionic liquid-assisted cloud point extraction for enrichment of trace copper(II) in water and food samples prior to spectrophotometric determination. [PDF]

Sci Rep
El-Bialy NMA, Gouda AA, Ghaith EIA, Khedr IE, Moustafa AH, Mohamed AA, Ismaiel AM.   +6 more
europepmc   +1 more source

Mixed modules over valuations rings [PDF]

Pacific Journal of Mathematics, 1960
openaire   +2 more sources