Results 51 to 60 of about 416,389 (287)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Valuation theory of exponential Hardy fields I [PDF]
Let \(T\) be a theory of a polynomially bounded o-minimal expansion \({\mathcal P}\) of the ordered field of reals. Let \({\mathcal F}_T\) be the set of all o-definable functions of \({\mathcal P}\). It is assumed that \(T\) defines the restricted exponential and logarithmic functions.
Kuhlmann, Franz-Viktor, Kuhlmann, Salma
openaire +4 more sources
Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Analysis of Interbrand, BrandZ and BAV brand valuation methodologies [PDF]
Brand valuation is considered for one of the most significant challenges of not only theory and practice of contemporary marketing, but other disciplines, as well.
Krstić Bojan, Popović Ana
doaj +1 more source
Milnor K-theory of complete discrete valuation rings with finite residue fields
Consider a complete discrete valuation ring $\mathcal{O}$ with quotient field $F$ and finite residue field. Then the inclusion map $\mathcal{O} \hookrightarrow F$ induces a map $\hat{\mathrm{K}}^\mathrm{M}_*\mathcal{O} \to \hat{\mathrm{K}}^\mathrm{M}_*F$
Dahlhausen, Christian
core +1 more source
Lattices of paths: Representation theory and valuations [PDF]
We study some distributive lattices arising in the combinatorics of lattice paths. In particular, for the Dyck, Motzkin and Schroder lattices we describe the spectrum and we determine explicitly the Euler characteristic in terms of natural parameters of lattice paths.
FERRARI, LUCA, E. Munarini
openaire +4 more sources

