Results 191 to 200 of about 9,110,558 (300)

Bioprocessing of Grape Pomace for Value Added Ingredients with Utilization in Baked Products. [PDF]

Foods
Zmuncilă A, Pop CR, Fărcaş AC, Man SM, Chiș MS, Lițoiu A, Păucean A.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Development of Value-Added Food Products from European Catfish (<i>Silurus glanis</i>) to Support Its Valorisation and Capture in the Tagus River, Portugal. [PDF]

Foods
Reis J, Antunes IC, Lima GB, Ribeiro AT, Neves A, Roseiro LC, Alvarenga N, Gonçalves H, Fernandes J, Silva M, Gonçalves EM, Gomes SF, Lageiro M, Soares A, Pinto P, Dias I.   +15 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Enhancing the Value Added of Lignin Extracted from <i>Pinus massoniana</i> Lamb. via DES Pretreatment. [PDF]

Polymers (Basel)
Cheng H, Yuan TQ, Cheng J, Zhan Y, Zhou X, Fang G, Deng Y.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Compartmentalized Liquid Microenvironments of Pickering Emulsion Droplets for Continuous-Flow Catalysis

JACS Au
Peng Yang, Yahong Yao, Rammile Ettelaie, Yumeng Mi, Nan Xue, Anpeng Hu, Ming Zhang, Hengquan Yang   +7 more
doaj   +1 more source

High Value-Added Secondary Raw Material From Winemaking Waste Bentonite to Design Antioxidant Pectin-Based Mucoadhesive Buccal Films. [PDF]

ChemistryOpen
Di Prima G, La Mantia C, De Caro V.
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Microbial decontamination and enhanced extraction of value-added compounds from Spirulina platensis using gamma radiation. [PDF]

World J Microbiol Biotechnol
Ali HEA, Abd El-Al MS, Moussa MM, Gomaa OM, Hassan KA, El-Fayoumy EA.   +5 more
europepmc   +1 more source