Results 141 to 150 of about 49,838,108 (340)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Estimation of Value at Risk and Conditional Value at Risk
Estimation of Value at Risk and Conditional Value at Risk【学位授与の要件】中央大学学位規則第4条第1項 【論文審査委員主査】石村 直之(中央大学商学部教授) 【論文審査委員副査】斎藤 正武(中央大学商学部教授),髙岡 浩一郎(中央大学商学部教授) application ...
openaire +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review. [PDF]
Eur Respir Rev, 2023 Singh SJ +8 more
europepmc +1 more source
Comparisons of cashflow maps for value-at-risk [PDF]
This article is devoted to the study cashflow maps used in the computation of value-at-risk (VaR). Properties and characteristics of the approaches found in the literature are presented and two new approaches are introduced.
Henrard Marc
core
Value-at-Risk for folded normal (black) and folded t (red) distributions.
, 2016 Value-at-Risk for folded normal (black) and folded t (red) distributions.
Shaiful Anuar Abu Bakar (2822411) +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Machine learning-based price forecasting and risk management in renewable energy markets
Sustainable Energy ResearchThe rising share of renewable energy has amplified electricity price volatility, underscoring the need for accurate forecasting and robust risk management.
Kuochun Lin, Peichun Feng
doaj +1 more source