Results 191 to 200 of about 49,838,108 (340)

Value-at-Risk Bounds with Variance Constraints

open access: yes, 2015
Carole Bernard   +2 more
semanticscholar   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Value at Risk (VaR) and the alpha-stable distribution [PDF]

open access: yes
Volatility in financial markets is a matter of considerable concern to financial institutions and their supervisors. Already it is clear that this volatility has had an adverse effect on the real economy.
John C. Frain
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Skeletal Muscle Gauge and Complementary Pan-Immune-Inflammation Value for Risk Stratification of 30-Day Major Complications After Colorectal Cancer Surgery. [PDF]

open access: yesBiomedicines
Kiss BI   +11 more
europepmc   +1 more source

Beyond Value‐at‐Risk: GlueVaR Distortion Risk Measures

open access: yesRisk Analysis, 2014
Jaume Belles-Sampera   +2 more
semanticscholar   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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