Results 141 to 150 of about 1,909,523 (262)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Slouching Toward Value-Based Health Care [PDF]

Health Affairs, 2008
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Costs in value-based health care dashboards: a qualitative study on stakeholder requirements. [PDF]

BMC Health Serv Res
van der Poort EKJ, van der Helm D, de Vries APJ, van den Hout WB, van den Akker-van Marle ME.   +4 more
europepmc   +1 more source

Opportunities and Challenges of Value-Based Health Care: How Brazil Can Learn from U.S. Experience. [PDF]

J Manag Care Spec Pharm, 2020
Abicalaffe C, Schafer J.
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Digital Health Innovations to Catalyze the Transition to Value-Based Health Care. [PDF]

JMIR Med Inform
Zhang L, Bullen C, Chen J.
europepmc   +1 more source

Seeding the value based health care and standardised measurement of quality of life after burn debate. [PDF]

Burns, 2020
Edgar DW, Van Daele U, Spronk I, van Baar M, van Loey N, Wood FM, Kazis LB, Meirte J.   +7 more
europepmc   +1 more source