Results 131 to 140 of about 943,042 (302)

VALUATION EFFECTS OF ACCOUNTING INFORMATION AVAILABILITY [PDF]

open access: yes
In this paper, we extend comparative value relevance research by examining patterns in the value relevance of accounting numbers as a function of the month in which market values are observed.
Grzegorz Szafrański   +1 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The effects of accounting standards on earnings management and value relevance : a case of Malaysian and Nigerian banks [PDF]

open access: yes, 2015
The mandatory adoption of IFRS beginning from January 1st 2005 by European Union listed firms has attracted contradictory but limited results from emerging economies, particularly, banking sector on the potency of its adoption in reducing earnings ...
Ugbede, Onalo
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

HIV testing in Europe: Evaluating the impact, added value, relevance and usability of the European Centre for Disease Prevention and Control (ECDC)'s 2010 HIV testing guidance. [PDF]

open access: yesEuro Surveill, 2017
Sullivan AK   +7 more
europepmc   +1 more source

DIFFERENTIAL CHANGES IN THE VALUE-RELEVANCE OF EARNINGS AND BOOK VALUES OVER TIME: FINANCIAL VERSUS OTHER INDUSTRIES [PDF]

open access: yes
We investigate the change in the value-relevance of earnings and book value information in the financial industry compared to other industries from 1970 to 2005.
Lucy Huajing Chen, Sharad Asthana
core  

PENGARUH ADOPSI IFRS TERHADAP RELEVANSI NILAI DAN KETEPATWAKTUAN PENGAKUAN KERUGIAN PERUSAHAAN DI INDONESIA [PDF]

open access: yes, 2016
This study aims to examine the effects of IFRS adoption on value relevance and timely loss recognition of company in Indonesia. This study aims also to examine the effects of IFRS adoption on value relevance and timely loss recognition for company in ...
BENING, Annisa, JULIARTO, Agung
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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