Results 221 to 230 of about 22,957,355 (293)

A benchmarking of genomic selection models for predicting grain-yield related traits using haplotype-based and genome-wide association study-based markers in rice. [PDF]

Plant Genome
Hu X, Xian L, Cao G, Liu S, Wang D, Che Y, Huang W, Lin Y, He L.   +8 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Value-added assessment of career planning for vocational competence based on deep learning. [PDF]

Sci Rep
Zhang W.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Influence of equity structure in China's high-tech manufacturing industry on enterprise value under epidemic shocks. [PDF]

Sci Rep
Yao J, Jiang Q.
europepmc   +1 more source

Behavioural nudges to reduce low-value care for low back pain in the emergency department (NUDG-ED): a 2 × 2 factorial, pragmatic cluster randomized trial. [PDF]

CMAJ
Altinger G, Sharma S, Maher CG, Cullen L, McCaffery K, Linder JA, Buchbinder R, Harris IA, Coiera E, MBiostat QL, Devaux A, Howard K, Coggins A, Middleton PM, Gunja N, Ferguson I, Chan T, Mallows J, Darby S, Tambree K, van Wyk A, Traeger AC, NUDG-ED Study Group.   +22 more
europepmc   +1 more source

Nutritional-Inflammatory Recovery After Metal versus Plastic Biliary Stenting in Elderly Cholangiocarcinoma: A Prospective Observational Cohort Study. [PDF]

Clin Interv Aging
Li C, Zhang N, Ren H.
europepmc   +1 more source

Correction: The Natural History of Acanthamoeba Keratitis: A Systematic Literature Review

Ophthalmology and Therapy
Vincenzo Papa, Danielle H. Bodicoat, Angela Arteaga Duarte, John K. G. Dart, Maria De Francesco   +4 more
doaj   +1 more source