Results 11 to 20 of about 3,066,509 (354)

Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy

open access: yesScientific Reports, 2021
Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating ...
Wen-Wei Lin   +12 more
doaj   +1 more source

Development and characterization of pH-sensitive chondroitin sulfate-co-poly(acrylic acid) hydrogels for controlled release of diclofenac sodium

open access: yesJournal of Saudi Chemical Society, 2021
The aim of the current study was to prepare pH-sensitive chondroitin sulfate-co-poly(acrylic acid) hydrogels (CSPAA-hydrogels) for controlled release of diclofenac sodium.
Muhammad Suhail   +2 more
doaj   +1 more source

Moderate-dose Regular Lifelong Alcohol Intake Changes the Intestinal Flora, Protects against Aging, and Keeps Spatial Memory in the Senescence-accelerated Mouse Prone 8 (SAMP8) Model

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2016
Purpose: Heavy and long-term alcohol consumption increase the risk of alcohol-related diseases. Epidemiological studies show moderate drinking reduces the risk of mortality, cardiovascular diseases, and brain infarction in the J-shaped or U-shaped curve ...
Chikako Shimizu   +4 more
doaj   +1 more source

Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe

open access: yesFrontiers in Microbiology, 2022
Hepatitis C virus (HCV) NS3/4A protease is an attractive target for direct-acting antiviral agents. Real-time tracking of the NS3/4A protease distribution and activity is useful for clinical diagnosis and disease management. However, no approach has been
Chih-Hung Chuang   +24 more
doaj   +1 more source

Value creation by Turkish enterprises [PDF]

open access: yes, 2006
This study focuses on the resurgence of the automotive and appliance sectors in Turkey’s recent years. The analysis of both these sectors reveals some interesting lessons about technology management and investment strategies for companies to invest in ...
Altintas, Nihat   +5 more
core   +1 more source

Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

open access: yesPharmacological Research, 2022
The bidirectional interaction between carcinogens and gut microbiota that contributes to colorectal cancer is complicated. Reactivation of carcinogen metabolites by microbial β-glucuronidase (βG) in the gut potentially plays an important role in ...
Kai-Wen Cheng   +13 more
doaj   +1 more source

Targeting and internalizing PEGylated nanodrugs to enhance the therapeutic efficacy of hematologic malignancies by anti-PEG bispecific antibody (mPEG × CD20)

open access: yesCancer Nanotechnology, 2023
Background PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect).
Huei-Jen Chen   +13 more
doaj   +1 more source

Properties Exploring and Information Mining in Consumer Community Network: A Case of Huawei Pollen Club

open access: yesComplexity, 2018
Substantial changes took place in the role of consumers in the supply chain with the development of practices. They became creators from consumers of product values.
Qingchun Meng   +3 more
doaj   +1 more source

Volitional Control of Piloerection: Objective Evidence and Its Potential Utility in Neuroscience Research

open access: yesFrontiers in Neuroscience, 2020
The volitional control of piloerection has been previously reported in a small subset of individuals. Although this ability may be useful to study the mechanism underlying piloerection, there is little existing research on this ability, neither objective
Kenji Katahira   +5 more
doaj   +1 more source

A study on the application prospect of functional shirt fabrics in the uniform industry

open access: yesMATEC Web of Conferences, 2017
This paper analyses the value of functional shirt fabrics in the application of uniform industry. Through the functional research of the professional wear shirt fabric, we analyzed the industry needs and demands strength, and on the basis of the analysis
Xue Xing, Wen Gu, Li Li, Xiaogang Liu
doaj   +1 more source

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