Results 11 to 20 of about 3,098,991 (308)

Value creation and CSR. [PDF]

J Bus Econ, 2023
A more robust, inclusive model of value creation will sharpen dominant normative theories of Corporate Social Responsibility (CSR) such as stakeholder theory and the theory of communicative/deliberative democracy. When measuring value creation, CSR theories oscillate between traditional, exchange-based approaches utilizing narrow financial metrics and ...
Donaldson T.
europepmc   +3 more sources

Golden berry 4β-hydroxywithanolide E prevents tumor necrosis factor α-induced procoagulant activity with enhanced cytotoxicity against human lung cancer cells

Scientific Reports, 2021
Inflammation in the tumor microenvironment is positively correlated with cancer progression and metastasis as well as the risk of thromboembolism in lung cancer patients.
Kan-Yen Hsieh, Ju-Ying Tsai, Ya-Han Lin, Fang-Rong Chang, Hui-Chun Wang, Chin-Chung Wu   +5 more
doaj   +1 more source

Tris-(2-pyridyl)-pyrazolyl Borate Zinc(II) Complexes: Synthesis, DNA/Protein Binding and In Vitro Cytotoxicity Studies

Molecules, 2021
Zn(II) complexes bearing tris[3-(2-pyridyl)-pyrazolyl] borate (Tppy) ligand (1–3) was synthesized and examined by spectroscopic and analytical tools. Mononuclear [TppyZnCl] (1) has a Zn(II) centre with one arm (pyrazolyl-pyridyl) dangling outside the ...
Manmath Narwane, Dorothy Priyanka Dorairaj, Yu-Lun Chang, Ramasamy Karvembu, Yu-Han Huang, Hsueh-Wei Chang, Sodio C. N. Hsu   +6 more
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Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats

Cells, 2021
Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia.
Yu-Chi Cheng, Yu-Min Chiu, Zen-Kong Dai, Bin-Nan Wu   +3 more
doaj   +1 more source

Double attack strategy for leukemia using a pre-targeting bispecific antibody (CD20 Ab-mPEG scFv) and actively attracting PEGylated liposomal doxorubicin to enhance anti-tumor activity

Journal of Nanobiotechnology, 2021
Background Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization.
Kai-Wen Ho, I.-J.u Chen, Yi-An Cheng, Tzu-Yi Liao, En-Shuo Liu, Huei-Jen Chen, Yun-Chi Lu, Yu-Cheng Su, Steve R. Roffler, Bo-Cheng Huang, Hui-Ju Liu, Ming-Yii Huang, Chiao-Yun Chen, Tian-Lu Cheng   +13 more
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BK_Ca Channel Inhibition by Peripheral Nerve Injury Is Restored by the Xanthine Derivative KMUP-1 in Dorsal Root Ganglia

Cells, 2021
This study explored whether KMUP-1 improved chronic constriction injury (CCI)-induced BKCa current inhibition in dorsal root ganglion (DRG) neurons. Rats were randomly assigned to four groups: sham, sham + KMUP-1, CCI, and CCI + KMUP-1 (5 mg/kg/day, i.p.)
Kuang-I Cheng, Kan-Ting Yang, Chien-Lun Kung, Yu-Chi Cheng, Jwu-Lai Yeh, Zen-Kong Dai, Bin-Nan Wu   +6 more
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Influence of Housing Systems on Physical, Emotional, and Cognitive Functions with Aging in DBA/2CrSlc Mice

Animals, 2020
Environmental conditions, including enrichment and stress, affect animal behaviors, but limited information is available regarding the differences in animal functions between the chamber (ventilated system) vs. IVC (individually ventilated cages) housing
Chikako Shimizu, Yoshihisa Wakita, Youichi Tsuchiya, Toshitaka Nabeshima   +3 more
doaj   +1 more source

Fibrinogen-Like Protein 1 Serves as an Anti-Inflammatory Agent for Collagen-Induced Arthritis Therapy in Mice

Frontiers in Immunology, 2021
Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune homeostasis.
Wen-Wei Lin, Wen-Wei Lin, Wen-Wei Lin, Wen-Wei Lin, Wen-Wei Lin, Kai-Wen Ho, Hsiang-Han Su, Tien-Fang Fang, Shey-Cherng Tzou, Shey-Cherng Tzou, I-Ju Chen, Yun-Chi Lu, Mu-Shen Chang, Yun-Chen Tsai, En-Shuo Liu, Yu-Cheng Su, Yu-Cheng Su, Yen-Tseng Wang, Yen-Tseng Wang, Tian-Lu Cheng, Tian-Lu Cheng, Tian-Lu Cheng, Hsin-Kai Huang   +22 more
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Erratum: Chikako, S.; Yoshihisa, W.; Youichi, T.; Toshitaka, N. Influence of Housing Systems on Physical, Emotional, and Cognitive Functions with Aging in DBA/2CrSlc Mice Animals 2020, 10, 746

Animals, 2020
The authors wish to make the following corrections to their paper [...]
Chikako Shimizu, Yoshihisa Wakita, Youichi Tsuchiya, Toshitaka Nabeshima   +3 more
doaj   +1 more source

Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy

Scientific Reports, 2021
Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating ...
Wen-Wei Lin, Yi-An Cheng, Chia-Ching Li, Kai-Wen Ho, Huei-Jen Chen, I.-J.u Chen, Bo-Cheng Huang, Hui-Ju Liu, Yun-Chi Lu, Chiu-Min Cheng, Ming-Yii Huang, Hung-Wen Lai, Tian-Lu Cheng   +12 more
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