Results 141 to 150 of about 3,582,587 (303)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Analysis of the intrinsic value of life in the context of synthetic biology. [PDF]

Front Bioeng Biotechnol
Zhang Y, Chen Y, Liao B.
europepmc   +1 more source

Is "end of life" a special case? Connecting Q with survey methods to measure societal support for views on the value of life-extending treatments. [PDF]

Health Econ, 2018
Mason H, Collins M, McHugh N, Godwin J, Van Exel J, Donaldson C, Baker R.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The value of the world's ecosystem services and natural capital

Nature, 1997
R. Costanza, R. D'arge, R. Groot, S. Farber, M. Grasso, B. Hannon, K. Limburg, Shahid Naeem, R. O'Neill, J. Paruelo, R. Raskin, P. Sutton, M. Belt   +12 more
semanticscholar   +1 more source

Identifying a Terminal Nickel–Oxygen Complex Bearing an Unsymmetrical β‑Diketiminate Ligand

JACS Au
Si-Hong Chen, Tzu-Hsien Yang, Yu-Lun Chang, Wei-Syuan Lin, Chuan-Hung Chuang, Cheng-Han Yang, Hsing-Yin Chen, Ming-Li Tsai, Sodio C. N. Hsu   +8 more
doaj   +1 more source

The Way Older Childless Women Value Their Life-A Qualitative Study. [PDF]

Behav Sci (Basel)
Boker Gonen T, Bachner YG, Slonim-Nevo V.   +2 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Kipling's Values in Life: An Epitome of Ethics and Values of Life

The present social scenario of the world portrays the evil and wicked actions of man, which destroy the peace of man. The saints, priests and every religion in the world preach values of life, as it has become need of the hour. Despite of the advancement in the modern technology and other artificial resources, the entire world is suffering either from ...
openaire   +1 more source