Results 111 to 120 of about 7,746,809 (293)
Audit quality and the value relevance of fair values
Peer ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Medical research plays a crucial role in advancing our understanding of various aspects related to health, including disease, risk factors, and patient management.
Yousif AbdulRaheem
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Clean Surplus Accounting: Value Relevance of Book Value and Earnings [PDF]
This study attempts to predict future stock returns by return on owner’s equity ratio (ROE) namely, earning to equity book value ratio and its variability both in company level and in portfolio level.
ویدا مجتهد زاده +2 more
doaj
Value relevance of ESG: Is ESG performance value relevant for stock prices in Europe?
Master i økonomi og ...
Kirkerud, Sina, Tran, Kim Theresa
openaire +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Le attività immateriali: disciplina contabile, disclosure e value relevance.
Il volume analizza le attività immateriali, soffermandosi sulla disciplina contabile, sugli strumenti di rendicontazione volontaria e verificandone la value relevance.
COLUCCIA, DANIELA
core

