Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Value Relevance of Dirty Surplus Accounting Flows in the Netherlands [PDF]
Recently the Dutch financial reporting standard setters have taken steps to make dirty surplus accounting flows more visible to parties outside firms, either by eliminating their possibility or by requiring comprehensive income type statements.
Buijink, W.F.J. +2 more
core
This study examines the impact of engaging valuation specialists on the value relevance of Level 3 fair value measurements (FVMs) within the auditing process.
Yao, Daifei +3 more
core +1 more source
Characterization of Drugs with Good Glass Formers in Loaded-Mesoporous Silica and Its Theoretical Value Relevance with Mesopores Surface and Pore-Filling Capacity. [PDF]
Budiman A, Aulifa DL.
europepmc +1 more source
Valuing as a social process: Embodiment, relevance, and commensuration
In Inventing Value, Dave Elder-Vass (2022) argues that value is a set of beliefs about items that are strategically propagated to increase profits. The emphasis on value as a social process is particularly welcome, as this is the most fruitful direction for understanding worth. But the book leaves most of the important questions unanswered: who or what
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Value relevance of comprehensive income and its components: Evidence from major European capital markets. [PDF]
This study investigates the extent to which three key summary accounting income figures, namely operating income, net income and comprehensive income, provide value-relevant information to investors in Germany, France, Italy, Spain and the UK.
Casta, Jean-François +2 more
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
THE VALUE OF RELEVANCE THEORY IN LITERARY ANALYSIS [PDF]
Artikel ini mengkaji pandangan Formalist Linguistics dan Relevance Theory terhadap karya sastra. Formalist Linguistics berpandangan bahwa nilai sebuah karya sastra terletak pada keistimewaan bahasanya.
Candria, Mytha
core +1 more source

