Results 41 to 50 of about 114,439,094 (292)

A computational fluid dynamics evaluation of a pneumatic safety relief valve [PDF]

, 2008
Safety relief valves are well established components preventing catastrophic failure of pressurised systems when non-normal operating conditions occur.
Dempster, W.M., Elmayyah, W.
core   +3 more sources

A meta‐analysis of valve‐in‐valve and valve‐in‐ring transcatheter mitral valve implantation [PDF]

Journal of Interventional Cardiology, 2018
ObjectivesWe performed a meta‐analysis of transcatheter mitral valve implantation (TMVI) for deteriorated bioprosthetic valves (valve‐in‐valve [VIV]‐TMVI) and/or failed annuloplasty rings (valve‐in‐ring [VIR]‐TMVI), comparing observed early (30‐day) mortality with predicted operative mortality.BackgroundIt remains unclear whether VIV/VIR‐TMVI reduces ...
Hisato, Takagi, Yosuke, Hari, Norikazu, Kawai, Tomo, Ando   +3 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Local versus general anesthesia for transcatheter aortic valve implantation (TAVR)- systematic review and meta-analysis [PDF]

, 2014
The hypothesis of this study was that local anesthesia with monitored anesthesia care (MAC) is not harmful in comparison to general anesthesia (GA) for patients undergoing Transcatheter Aortic Valve Implantation (TAVR).TAVR is a rapidly spreading ...
Webb, J, Reinthaler, M, Georg M Fröhlich, Marco Roffi, Olaf Wendler, Nevil Hutchinson, Markus Reinthaler, Duolao Wang, David Hildick-Smith, Wang, D, Hutchinson, N, Fröhlich, GM, John Webb, Pascal Meier, Alexandra J Lansky, Wendler, O, Hildick-Smith, D, Stefan Toggweiler, Lansky, AJ, Roffi, M, Meier, P, Toggweiler, S   +21 more
core   +2 more sources

Microflow valve control system design [PDF]

, 2011
A design synthesis for a microflow control system is presented based on the interrogation of an analytical model, testing, and observation. The key issues relating to controlling a microflow using a variable geometry flow channel are explored through the
Zante, Remi Christophe, Yan, Xiu
core   +4 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Double orifice mitral valve associated with Ventricular Septal Defect in an infant : case report [PDF]

, 2011
Double orifice mitral valve (DOMV) is an uncommon anomaly characterized by a mitral valve with a single fibrous annulus with two orifices opening into the left ventricle.
Taksande, Amar M., Thomas, E., Goutami, V.   +2 more
core  

Valve-in-valve procedures for degenerated surgical and transcatheter aortic valve bioprostheses using a latest-generation self-expanding intra-annular transcatheter heart valve

Frontiers in Cardiovascular Medicine, 2023
BackgroundValve-in-valve (ViV) transfemoral transcatheter aortic valve implantation (TAVI) for failing aortic surgical bioprostheses or transcatheter heart valves (THV) has demonstrated a reasonable clinical and hemodynamic efficacy.
Andreas Schaefer, Till Joscha Demal, Oliver D. Bhadra, David Grundmann, Lisa Voigtländer, Lara Waldschmidt, Johannes Schirmer, Simon Pecha, Yvonne Schneeberger, Niklas Schofer, Nils Sörensen, Stefan Blankenberg, Hermann Reichenspurner, Moritz Seiffert, Lenard Conradi   +14 more
doaj   +1 more source

Mitral valve‐in‐valve and valve‐in‐ring procedures: Midterm outcomes in a French nationwide registry

Catheterization and Cardiovascular Interventions, 2022
AbstractObjectivesReport contemporary outcomes in patients included in the Mitragister registry and treated with transcatheter mitral valve implantation for failed surgical annuloplasty rings or deteriorated bioprosthesis.BackgroundMidterm survival rates have been reported, but little is known about contemporary morbimortality endpoints.MethodsThe ...
Robin Le Ruz, Patrice Guérin, Guillaume Leurent, Lionel Leroux, Thierry Lefevre, Mohammed Nejjari, Didier Champagnac, Didier Tchétché, Thibault Lhermusier, Thomas Senage, Pierre‐Guillaume Piriou, Christophe Caussin, Maxence Delomez, Guillaume Bonnet, Xavier Favereau, Nicole Karam, Antoine Gerbay, Francis Juthier, Martine Gilard, Jean‐Francois Obadia, Bernard Iung, Thibaut Manigold   +21 more
openaire   +4 more sources

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source