Results 151 to 160 of about 130,598 (314)

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science, EarlyView.
ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
wiley   +1 more source

Transesophageal Echocardiography in Transcatheter Mitral Valve Replacement. [PDF]

J Clin Med
Bacchi B, Derry K, Vira T, Alnasser S, Montanhesi PK, Fam N, Bisleri G.   +6 more
europepmc   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Simultaneous transcatheter aortic and mitral valve-in-valve replacement: A case report. [PDF]

Medicine (Baltimore)
Mao Y, Zhan Y, Li R, Chen J, Mo Q.
europepmc   +1 more source

Curved Bistable Origami‐Inspired Flexible Transcatheter Mitral Valve Clamping

Advanced Science, EarlyView.
A lightweight bistable curved origami dilator combines reversible deformation and high stability, offering a promising solution for minimally invasive mitral valve repair. Abstract Curved origami exhibits remarkable potential for minimally invasive medical applications owing to its unique geometric programmability and mechanical tunability. Building on
Siyu Gao, Fan Jiang, Xiuting Sun, Peng Qi, Jian Xu   +4 more
wiley   +1 more source

Transcatheter aortic valve replacement in patients with previous mitral valve replacement. A systematic study

Advances in Interventional Cardiology, 2020
Zbigniew Chmielak, Maciej Dąbrowski, Paweł Tyczyński, Krzysztof Kukuła, Ilona Michałowska, Emilia Szudejko, Jarosław Skowroński, Mariusz Kuśmierczyk, Adam Witkowski   +8 more
doaj   +1 more source

Surgical remodeling techniques for the right ventricle during pulmonary valve replacement. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Altın HF, Özdemir DM, Özkök S, Altunyuva K, Erdem H.   +4 more
europepmc   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Feasibility of Valve in Valve After Transcatheter Aortic Valve Replacement With SAPIEN 3 Valves and Surgical Aortic Valve Replacement. [PDF]

Struct Heart
Sheth T, Al-Shamkani W, Makhdoum A, Viquez JC, Suleman M, Dick A, Sathananthan J, Wood D, Fam N, AlRaddadi H, Natarajan MK, Velianou JL.   +11 more
europepmc   +1 more source

Surgical Aortic Valve Replacement For Bicuspid And Tricuspid Valve Disease: 7-Year Outcomes In >1100 Patients

Louis Labrousse, Michael G. Moront, François Dagenais, Michael J. Reardon, G. Michael Deeb, Ralf Günzinger, Marc Ruel, Tianhua Wu, Robert J.M. Klautz, Joseph F. Sabik   +9 more
openalex   +1 more source