Induction of Myocarditis and Valvuluitis in Lewis Rats by Different Epitopes of Cardiac Myosin and its Implications in Rheumatic Carditis [PDF]
Immune responses against cardiac myosin and group A streptococcal M protein have been implicated in the pathogenesis of rheumatic heart disease.
Cunningham, Madeleine W. +5 more
core
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Effect of coenzyme q10 supplementation on total antioxidant status and lipid peroxides levels in dogs with chronic valvular heart disease* [PDF]
Oxidativestressmanagementhasbeenfoundtohavebeneficialeffects in the management of several disease conditions. A study was conducted to evaluate the efficacy of Coenzyme Q10 supplementation on the total antioxidant status and lipid peroxides levels in ...
K. Revathi +4 more
doaj
Edible Pneumatic Battery for Sustained and Repeated Robot Actuation
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak +5 more
wiley +1 more source
Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen +11 more
wiley +1 more source
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar +8 more
wiley +1 more source
Culture Positive Brucella Endocarditis in a Case of Baloon Mitral Valvotomy [PDF]
Brucella endocarditis is a rare condition which occurs as a focal complication in chronic brucellosis cases. We report a rare brucella endocarditis case in a RVHD patient. A 26 years old male was admitted with fever on off for almost one year.
Aundhkar, S, Ghorpade, MV, Pawar, SK
core
1004Impact of ischemic and valvular heart disease on atrial excitation: a high-resolution epicardial mapping study [PDF]
Elisabeth M.J.P. Mouws +9 more
openalex +1 more source
Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell–Cell Interactions
This work presents a single‐target pairing system, StarPair, enabling cell–cell interaction studies by target combination in droplets. StarPair offers superior pairing efficiencies over 95% and operation frequencies of 105 pairs per 9.5 h for two‐target pairing, allowing large‐scale interrogation of immune cell‐cancer cell interactions and precise ...
Tianjiao Mao +6 more
wiley +1 more source
New oral anticoagulants and their reversal agents [PDF]
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana +9 more
core +1 more source

