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Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association

Circulation
Valvular heart disease is a common cause of morbidity and mortality worldwide and has no effective medical therapy. Severe disease is managed with valve replacement procedures, which entail high health care–related costs and postprocedural morbidity and ...
Aeron M. Small   +8 more
semanticscholar   +1 more source

Global, Regional, and National Burden of Valvular Heart Disease, 1990 to 2021

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease
Background Valvular heart disease poses an escalating global health challenge with an increasing impact on mortality and disability. This study aims to comprehensively analyze the global burden of valvular heart disease.
Qin-Fen Chen   +10 more
semanticscholar   +1 more source

Valvular Heart Disease

New England Journal of Medicine, 1997
M S, Feinberg   +2 more
  +7 more sources

CT of valvular heart disease

The International Journal of Cardiovascular Imaging, 2005
Although the incidence of valvular heart disease is significantly less than before the introduction of antibiotic therapy, chronic mitral and aortic valve disease continues to be found in the adult population. CT examination reveals characteristic chamber volume and myocardial mass changes expected in patients with valvular obstruction and ...
openaire   +2 more sources

Valvular heart disease in pregnancy

Best Practice & Research Clinical Obstetrics & Gynaecology, 2014
In women with valvular heart disease, pregnancy-associated cardiovascular changes can contribute to maternal, foetal and neonatal complications. Ideally, a woman with valvular heart disease should receive preconception assessment and counselling from a cardiologist with expertise in pregnancy.
Jonathan D, Windram   +5 more
openaire   +2 more sources

Acute Valvular Heart Disease

Cardiology Clinics, 2018
Valvular heart disease (VHD) is a common clinical entity. Recognition of decompensated VHD is crucial to instituting appropriate workup and management. Initial evaluation focuses on hemodynamics, peripheral perfusion, volume overload, and active myocardial ischemia.
Varun, Maheshwari   +2 more
openaire   +2 more sources

Valvular Heart Disease and Pregnancy

Current Treatment Options in Cardiovascular Medicine, 2018
With improving reproductive assistive technologies, advancing maternal age, and improved survival of patients with congenital heart disease, valvular heart disease has become an important cause of morbidity and mortality in pregnant women. In general, stenotic lesions, even those in the moderate range, are poorly tolerated in the face of hemodynamic ...
Emily S, Lau, Nandita S, Scott
openaire   +2 more sources

Endothelium and valvular diseases of the heart

Microscopy Research and Technique, 2003
AbstractIt has become increasingly evident that the endothelium plays a critical role in the pathogenesis of valvular heart disease. The endothelium helps regulate vascular tone, inflammation, thrombosis, and vascular remodeling. Dysfunction of the endothelial cells has been linked to many vascular disorders including atherosclerosis.
Richard L, Leask   +2 more
openaire   +2 more sources

Echocardiography in valvular heart disease

Current Opinion in Cardiology, 1992
Last year alone, more than 140 reports on echocardiography and its different technical modalities (M-mode, two-dimensional, transesophageal, intraoperative, Doppler, and so forth.) in valvular heart disease were published in peer-reviewed journals.
H G, Klues, P, Hanrath
openaire   +2 more sources

Echocardiography in valvular heart disease

Current Opinion in Cardiology, 1994
Transthoracic Doppler echocardiography continues to play a predominant role in the evaluation of patients with valvular heart disease. Current efforts in the research arena have been focused on improving the accuracy of techniques, as well as in further describing the shortcomings. Accurate quantitation of valvular regurgitation continues to be a major
openaire   +2 more sources

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