Results 81 to 90 of about 18,080,110 (353)

The Impact of Climate Change on Mental Health: A General Population Study

European Psychiatry
Introduction Climate change and its impact on mental health is a growing area of research. Several studies have explored the relationship between climate change and mental health, highlighting the various ways in which climate change can affect ...
R. Uçak, C. H. Ayhan, M. C. Aktaş, N. Kaynar Demirel   +3 more
doaj   +1 more source

Photovoltaic Effect in an Electrically Tunable van der Waals Heterojunction [PDF]

Nano letters (Print), 2014
Semiconductor heterostructures form the cornerstone of many electronic and optoelectronic devices and are traditionally fabricated using epitaxial growth techniques.
M. Furchi, A. Pospischil, F. Libisch, J. Burgdörfer, T. Mueller   +4 more
semanticscholar   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Etiopathogenesis of Acne Vulgaris

Van Tıp Dergisi, 2018
Acne vulgaris is a disease of pilosebase unity which is seen generally in adolesans. Clinically lesions may appear chest, back and face and they can be mild comedonal form to cystic acne. The primary lesions of acne is comedon.
Sema Elibüyük Aksaç, Serap Güneş Bilgili, İbrahim Halil Yavuz, Göknur Özaydın Yavuz   +3 more
doaj   +1 more source

Two-dimensional antimonene single crystals grown by van der Waals epitaxy

Nature Communications, 2016
Unlike the unstable black phosphorous, another two-dimensional group-VA material, antimonene, was recently predicted to exhibit good stability and remarkable physical properties.
Jianping Ji, Xiufeng Song, Jizi Liu, Zhong Yan, Chengxue Huo, S. Zhang, Meng Su, L. Liao, Wenhui Wang, Zhenhua Ni, Y. Hao, H. Zeng   +11 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The effects of pulse stimulation on biota - Research in relation to ICES advice - Effects on dogfish [PDF]

, 2009
Onderzoek naar het welzijn van hondshaaien bij de vangst. Er is onderzocht of de methode van het gebruik van stroom wel diervriendelijk is.
Haan, D., de, Heul, J.W., van der, Marlen, B., van, Velzeboer, I., Vis, J.W., van de   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Age-Based Dismissals After Retirement: Motor Industry Staff Association and Another v Great South Africa Autobody CC t/a Great South Panelbeaters & Solidarity obo Gerhardus Viljoen Strydom and Others v State Information Technology Agency Soc Limited [2024] ZACC 29

De Jure
The Constitutional Court’s judgment in Motor Industry Staff Association addressed whether employers can fairly dismiss employees based on age after they have worked beyond retirement age. The case consolidated two appeals: Landman, concerning an employee
Marthinus Van Staden
doaj   +1 more source