Results 101 to 110 of about 357,993 (360)

Short-periodic VLF emissions observed simultaneously by Van Allen Probes and on the ground

Geophysical Research Letters, 2021
AbstractWe present simultaneous observations of very low‐frequency emissions with periodic bursts by Van Allen Probe near geomagnetic equator and Kannuslehto and Lovozero ground‐based sites. The repetition period and ground–spacecraft delay are consistent with guided whistler wave propagation between conjugate ionospheres.
A. G. Demekhov, E. E. Titova, J. Manninen, A. S. Nikitenko, S. V. Pilgaev   +4 more
openaire   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Can We Intercalibrate Satellite Measurements by Means of Data Assimilation? An Attempt on LEO Satellites

Space Weather
Low Earth Orbit satellites offer extensive data of the radiation belt region, but utilizing these observations is challenging due to potential contamination and difficulty of intercalibration with spacecraft measurements at Highly Elliptic Orbit that can
Angélica M. Castillo, Yuri Y. Shprits, Nikita A. Aseev, Artem Smirnov, Alexander Drozdov, Sebastian Cervantes, Ingo Michaelis, Marina García Peñaranda, Dedong Wang   +8 more
doaj   +1 more source

Simulated magnetopause losses and Van Allen Probe flux dropouts [PDF]

Geophysical Research Letters, 2014
AbstractThree radiation belt flux dropout events seen by the Relativistic Electron Proton Telescope soon after launch of the Van Allen Probes in 2012 (Baker et al., 2013a) have been simulated using the Lyon‐Fedder‐Mobarry MHD code coupled to the Rice Convection Model, driven by measured upstream solar wind parameters.
Michael Wiltberger, Frank Toffoletto, Mary K. Hudson, J. Paral, Jerry Goldstein, Jerry Goldstein, Brian Kress, Daniel N. Baker   +7 more
openaire   +3 more sources

Modeling the Contribution of Precipitation Loss to a Radiation Belt Electron Dropout Observed by Van Allen Probes

Journal of Geophysical Research: Space Physics
A drift‐diffusion model is used to simulate the low‐altitude electron distribution, accounting for azimuthal drift, pitch angle diffusion, and atmospheric backscattering effects during a rapid electron dropout event on 21st August 2013, at L = 4.5 ...
Zhi‐Gu Li, W. Tu, R. Selesnick, Jinbei Huang   +3 more
semanticscholar   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

In situ observations of Pc1 pearl pulsations by the Van Allen Probes [PDF]

Geophysical Research Letters, 2014
We present in situ observations of Pc1 pearl pulsations using the Van Allen Probes. These waves are often observed using ground-based magnetometers, but are rarely observed by orbiting satellites. With the Van Allen Probes, we have seen at least 14 different pearl pulsation events during the first year of operations.
Roy B. Torbert, Roy B. Torbert, Charles W. Smith, Kristoff Paulson, Craig Kletzing, Mark J. Engebretson, Marc Lessard   +6 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Van Allen probes, NOAA, GOES, and ground observations of an intense EMIC wave event extending over 12 h in magnetic local time [PDF]

, 2015
Although most studies of the effects of EMIC waves on Earth's outer radiation belt have focused on events in the afternoon sector in the outer plasmasphere or plume region, strong magnetospheric compressions provide an additional stimulus for EMIC wave ...
Baker, D. N., Engebretson, M. J., Gkioulidou, M., Horne, R. B., Huang, C.-L., Kletzing, C. A., Lessard, M. R., Mann, I. R., Oksavik, K., Omura, Y., Posch, J. L., Raita, T ., Reeves, G. D., Shiokawa, K., Singer, H. J., Smith, C. W., Spence, H. E., Wygant, J. R.   +17 more
core   +1 more source

A Statistical Study of Lower Hybrid Waves in the Earth's Magnetosphere by Van Allen Probes

Geophysical Research Letters, 2021
AbstractThe lower hybrid (LH) waves are electrostatic emissions near the LH resonant frequency. They propagate perpendicularly with a small wavelength comparable to Larmor radius of thermal particles and can be capable of heating both ions and electrons.
Qianli Ma, Qianli Ma, Xu Liu, Lunjin Chen   +3 more
openaire   +2 more sources