Results 101 to 110 of about 129,844 (334)

Quasiperiodic Emissions: Fine Structure Corresponding to a Bouncing Wave

Geophysical Research Letters
Quasiperiodic (QP) emissions are whistler‐mode electromagnetic waves observed in the Earth's inner magnetosphere whose intensity has a nearly periodic time modulation with typical modulation periods on the order of minutes. Some events exhibit, on top of
F. Němec, O. Santolík, G. B. Hospodarsky, W. S. Kurth   +3 more
doaj   +1 more source

Quantifying the radiation belt seed population in the 17 March 2013 electron acceleration event [PDF]

, 2014
We present phase space density (PSD) observations using data from the Magnetic Electron Ion Spectrometer instrument on the Van Allen Probes for the 17 March 2013 electron acceleration event.
Baker, D. N., Blake, J. B., Boyd, A. J., Claudepierre, S., Fennell, Joseph F., Reeves, Geoffrey, Spence, Harlan E., Turner, D. L.   +7 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Cross Correlation Between Plasmaspheric Hiss Waves and Enhanced Radiation Levels at Aviation Altitudes

Space Weather
Enhanced radiation in the Earth's atmosphere can pose serious hazards to pilots, aircraft passengers, and commercial space travelers. Recent results have shown, statistically, that there is a strong correlation between dose rates observed by Automated ...
Homayon Aryan, Jacob Bortnik, W. Kent Tobiska, Piyush Mehta, Rashmi Siddalingappa, Benjamin Hogan   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Observations of Relativistic Electron Enhancement and Butterfly Pitch Angle Distributions at Low L (<3)

Geophysical Research Letters
Electrons in Earth's outer radiation belt are highly dynamic, with fluxes changing by up to orders of magnitude. The penetration of electrons from the outer belt to the inner belt is one such change observed during geomagnetic storms and was previously ...
D. O'Brien, X. Li, L. Khoo, R. S. Selesnick, B. Hogan, H. Zhao, Y. Mei, V. Hoxie, D. N. Baker, S. G. Kanekal   +9 more
doaj   +1 more source

Chorus Wave Properties From Van Allen Probes: Quantifying the Impact of the Sheath Corrected Electric Field

Geophysical Research Letters, 2023
A sheath impedance model has recently been developed to describe how the variable coupling impedance between the Van Allen Probes instrumentation and the ambient plasma affects both the amplitude and phase of electric field wave measurements.
D. P. Hartley, I. W. Christopher, C. A. Kletzing, W. S. Kurth, O. Santolik, I. Kolmasova, M. R. Argall, N. Ahmadi   +7 more
doaj   +1 more source

Simulations of inner magnetosphere dynamics with an expanded RAM-SCB model and comparisons with Van Allen Probes observations [PDF]

, 2014
Simulations from our newly expanded ring current-atmosphere interactions model with self-consistent magnetic field (RAM-SCB), now valid out to 9 R E, are compared for the first time with Van Allen Probes observations.
Fennell, Joseph F., Jordanova, Vania K., Kletzing, C A., Niehof, J. T., Reeves, Geoffrey, Skoug, R. M., Spence, Harlan E., Yu, Y.   +7 more
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

LaboratOry for the Behavior of the SloT Region: a small mission doing big radiation science

Frontiers in Astronomy and Space Sciences
This paper outlines the science and basic design choices associated with a mission concept study known as the LaboratOry for the Behavior of the SloT Region (LOBSTR).
Rachael Filwett, David Miles , Allison Jaynes , Christine Gabrielse   +3 more
doaj   +1 more source