Results 71 to 80 of about 129,844 (334)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Science Goals and Overview of the Radiation Belt Storm Probes (RBSP) Energetic Particle, Composition, and Thermal Plasma (ECT) Suite on NASA’s Van Allen Probes Mission [PDF]

, 2013
The Radiation Belt Storm Probes (RBSP)-Energetic Particle, Composition, and Thermal Plasma (ECT) suite contains an innovative complement of particle instruments to ensure the highest quality measurements ever made in the inner magnetosphere and radiation
Baker, D. N., Blake, J. B., Bolton, M., Bourdarie, S., Chan, A. A., Claudepierre, S. G., Clemmons, J. H., Cravens, J. P., Elkington, S. R., Fennell, J. F., Reeves, G. D., Spence, Harlan E.   +11 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Magnetic field fluctuations coinciding with substorm events

Earth, Planets and Space
Using observations from the Van Allen Probes spacecraft, this study reports multifrequency banded magnetic field fluctuations during substorm-associated magnetic field dipolarization at L < 6.6.
Trunali Shah, Veenadhari Bhaskara, Yoshiharu Omura, Biswajit Ojha, Satyavir Singh, Remya Bhanu, Yusuke Ebihara   +6 more
doaj   +1 more source

Ensemble modeling of long-term radiation belt dynamics: accounting for variability in radial diffusion

Frontiers in Astronomy and Space Sciences
This study presents ensemble modeling of outer radiation belt dynamics observed by Van Allen Probes throughout 2017 using DREAM3D simulations.
Sang-Yun Lee, Sang-Yun Lee, Weichao Tu, Gregory S. Cunningham, Gregory S. Cunningham, Misa M. Cowee   +5 more
doaj   +1 more source

Resonant scattering of energetic electrons by unusual low-frequency hiss [PDF]

, 2014
We quantify the resonant scattering effects of the unusual low-frequency dawnside plasmaspheric hiss observed on 30 September 2012 by the Van Allen Probes. In contrast to normal (∼100-2000 Hz) hiss emissions, this unusual hiss event contained most of its
Blake, J. B., Bortnik, J., Chen, Lunjin, Claudepierre, S., Fennell, Joseph F., Hospodarsky, G. B., Kletzing, C A., Kurth, W. S., Li, Wen, Ma, Qianli, Ni, Binbin, Reeves, Geoffrey, Spence, Harlan E., Thorne, R. M.   +13 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Effect of EMIC waves on relativistic and ultrarelativistic electron populations: Ground-based and Van Allen Probes observations [PDF]

, 2014
We study the effect of electromagnetic ion cyclotron (EMIC) waves on the loss and pitch angle scattering of relativistic and ultrarelativistic electrons during the recovery phase of a moderate geomagnetic storm on 11 October 2012.
A. Drozdov, A. Kale, Baker, Baker, C. Kletzing, Cornwall, D. K. Milling, D. L. Turner, D. N. Baker, Evans, G. D. Reeves, H. E. Spence, I. R. Mann, J. Wygant, K. Orlova, Kennel, Kessell, Kletzing, Li, M. E. Usanova, M. T. Robertson, Mann, Mann, Meredith, Rodger, S. A. Thaller, Shprits, Shprits, Spence, Summers, Summers, Tsyganenko, Ukhorskiy, Usanova, Usanova, Wygant, Y. Shprits   +36 more
core   +3 more sources

Statistical Analysis of Pi2 Pulsations Observed by Van Allen Probes

Journal of Geophysical Research: Space Physics, 2022
AbstractThe relative importance of propagating and cavity mode waves remains an important question regarding the generation of Pi2 pulsations detected on the ground. To determine the wave mode, we statistically generate spatial maps of magnetospheric oscillations that are coherent with ground Pi2 pulsations. The magnetospheric observations were made by
Kazue Takahashi, Robert Lysak, Massimo Vellante   +2 more
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source